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Caracterización clínica de familias costarricenses con trastorno afectivo bipolar
Clinical characterization of costarican families with bipolar disorder
(2014-12)
Justificación y objetivos: la heterogeneidad clínica del trastorno afectivo bipolar tipo I constituye
uno de los principales desafíos en el diagnóstico de dicha enfermedad. Se necesitan múltiples
fuentes de información ...
Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in latinos: a family-based association study
(Bipolar Disorders 2013: 15: 206–214, 2013-02-25)
Objectives: Through recent genome-wide association studies (GWASs),
several groups have reported significant association between variants in
the calcium channel, voltage-dependent, L-type, alpha 1C subunit
(CACNA1C) and ...
Identificación molecular de mutaciones asociadas con enfermedades mitocondriales
Molecular identification of mutations associated with mitochondrial diseases
(2014)
Las enfermedades mitocondriales se caracterizan por un defecto en el sistema de fosforilación oxidativa. Su espectro clínico es muy heterogéneo y se pueden originar por alteraciones en el ADN mitocondrial o nuclear. ...
The serotonin transporter 5-HTTPR polymorphism is associated with current and lifetime depression in persons with chronic psychotic disorders
(Acta Psychiatr Scand 2009: 119: 117–127, 2009-01-11)
Objective: Variation in the serotonin transporter gene (SLC6A4)
promoter region has been shown to influence depression in persons
who have been exposed to a number of stressful life events.
Method: We evaluated whether ...
Call for a change in research funding priorities: the example of mental health in Costa Rica
Solicitud de un cambio en las prioridades de financiamiento de la investigación: el ejemplo de la salud mental en Costa Rica
(2014)
The World Health Organization (WHO) Mental Health Action Plan 2013-2020 urges its Member States to strengthen leadership in mental health, ensure mental and social health interventions in community-based settings, promote ...