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Genetic structure of personality factors and bipolar disorder in families segregating bipolar disorder
(Journal of Affective Disorders xxx (2011) xxx–xxx, 2011)
Bipolar disorder (BPD) has been associated with variations in personality dimensions,
but the nature of this relationship has been unclear. Inthis study, theheritabilities of BPDandtheBig
Five personality factors and the ...
The serotonin transporter 5-HTTPR polymorphism is associated with current and lifetime depression in persons with chronic psychotic disorders
(Acta Psychiatr Scand 2009: 119: 117–127, 2009-01-11)
Objective: Variation in the serotonin transporter gene (SLC6A4)
promoter region has been shown to influence depression in persons
who have been exposed to a number of stressful life events.
Method: We evaluated whether ...
Diagnosis of Schizophrenia in Latino Populations. A Comparison of Direct Interview and Consensus Based Multi-Source Methods
(Journal of Nervous and Mental Disease 2009;197: 530–535, 2009-07)
We determined the rates of agreement between diagnoses, using
the Diagnostic Interview for Genetic Studies (DIGS) and diagnoses arrived
at, using additional sources of information, to establish whether there are
differences ...
The epsin 4 gene is associated with psychotic disorders in families of Latin American origin
(Schizophrenia Research vol. 106, num 2 (2008) 253–257, 2008-10-20)
This study attempted to replicate evidence for association of the Epsin 4 gene (which encodes
enthoprotin, a protein involved in vesicular transport) to schizophrenia in a new sample of
families segregating schizophrenia ...
Family-based association of an ANK3 haplotype with bipolar disorder in Latino populations
(Translational Psychiatry (2013) 3, e265, 2013-05-28)
Some of the most
consistent findings have been in variants located in the ANK3
(ankyrin-G) gene located on chromosome 10q. Schultz et al.4
found that BP risk alleles in ANK3, rs9804190 and
rs10994336, contributed ...
Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in latinos: a family-based association study
(Bipolar Disorders 2013: 15: 206–214, 2013-02-25)
Objectives: Through recent genome-wide association studies (GWASs),
several groups have reported significant association between variants in
the calcium channel, voltage-dependent, L-type, alpha 1C subunit
(CACNA1C) and ...
Heritability of Age of Onset of Psychosis in Schizophrenia
(AMERICAN JOURNAL OF MEDICAL GENETICS PART B, 2009-04)
Schizophrenia is a genetically complex illness with heterogeneous clinical presentation, including variable age ofonset. In this study, the heritability, or proportion of variation in age of onset of psychotic symptoms due ...