Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse
| dc.creator | Bultman, S. J. | |
| dc.creator | Russell, L. B. | |
| dc.creator | Gutiérrez Espeleta, Gustavo A. | |
| dc.creator | Woychik, R.P. | |
| dc.date.accessioned | 2015-10-22T22:34:54Z | |
| dc.date.available | 2015-10-22T22:34:54Z | |
| dc.date.issued | 1991-09-15 | |
| dc.description | Artículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 1991 | es |
| dc.description.abstract | Molecular characterization of a radiationinduced agouti (a)-locus mutation has resulted in the isolation of a segment of DNA that maps at or near the a locus on chromosome 2 in the mouse. This region of DNA is deleted in several radiation- or chemical-induced homozygous-lethal alocus mutations and is associated with specific DNA structural alterations in two viable a-locus mutations. We propose that DNA probes from this region of chromosome 2 will be useful for ultimately characterizing the individual gene or genes associated with a-locus function. | es |
| dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA) | es |
| dc.description.sponsorship | Universidad de Csta Rica, Instituto de Investigaciones en Salud. | es |
| dc.identifier.citation | http://www.pnas.org/content/88/18/8062.full.pdf | |
| dc.identifier.issn | 1091-6490 | |
| dc.identifier.issn | 0027-8424 | |
| dc.identifier.uri | https://hdl.handle.net/10669/15294 | |
| dc.language.iso | en_US | |
| dc.rights | acceso abierto | |
| dc.source | Proceedings of the National Academy of Sciences 88: 8062-8066 | es |
| dc.subject | agouti locus | es |
| dc.subject | mutaciones geneticas | es |
| dc.subject | estructura genética | es |
| dc.title | Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse | es |
| dc.type | artículo original |