Logo Kérwá
 

Mouse determinant lethal and bone marrow micronucleus studies on methyl vinyl sulfone and divinyl sulfone

dc.creatorShelby, Michael D.
dc.creatorGutiérrez Espeleta, Gustavo A.
dc.creatorGeneroso, Walderico M.
dc.creatorMcfee, A. F.
dc.date.accessioned2015-10-22T21:13:29Z
dc.date.available2015-10-22T21:13:29Z
dc.date.issued1991
dc.descriptionArtículo científico-- Instituto de Investigaciones en Salud-- 1991. La revista no permite distribuir la versión final del documento.es_ES
dc.description.abstractMethyl vinyl sulfone and divinyl sulfone were tested for the induction of dominant lethal mutations and micronucleated bone-marrow erythrocytes in male mice. These chemicals were chosen for study because of their similarities in structure and chemical reactivity to acrylamide which is known to induce both effects. Following administration of the test compounds by intraperitoneal injection at the maximum tolerated doses, no evidence of induced dominant lethal mutations or micronucleated bone-marrow cells was observed for either chemical. It is concluded that structures and Michael reactivities similar to acrylamide are not sufficient to impart similar in vivo genetic toxicity to MVS and DVS.es_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES
dc.description.sponsorshipUniversidad de Costa Rica, Instituto de Investigaciones en Salud.es_ES
dc.identifier.citationhttp://www.journals.elsevier.com/mutation-research-genetic-toxicology-and-environmental-mutagenesis/
dc.identifier.issn1383-5718
dc.identifier.urihttps://hdl.handle.net/10669/15290
dc.language.isoen_USes_ES
dc.rightsacceso embargado
dc.sourceMutation Reserch 250: 431-437es_ES
dc.subjectMethyl vinyl sulphonees_ES
dc.subjectDivinyl sulphonees_ES
dc.subjectDominant lethal mutationses_ES
dc.subjectBone marrow erythrocyteses_ES
dc.subjectMicronucleus studieses_ES
dc.subjectAcryiamidees_ES
dc.titleMouse determinant lethal and bone marrow micronucleus studies on methyl vinyl sulfone and divinyl sulfonees_ES
dc.typeartículo original

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
11 Mouse determinant lethal and bone marrow micronucleus studies on methyl vinyl sulfone and divinyl sulfone.pdf
Size:
2.58 MB
Format:
Adobe Portable Document Format
Description:
Versión final

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
2.38 KB
Format:
Item-specific license agreed upon to submission
Description: