Synthesis and Evaluation of Aromatic Surfactants as Potential Antibacterial and Cytotoxic Agents
| dc.creator | Barrantes Jiménez, Kenia | |
| dc.creator | Fuentes, Mary | |
| dc.creator | Chacón Jiménez, Luz María | |
| dc.creator | Achí Araya, María Rosario | |
| dc.creator | Vázquez Tato, José | |
| dc.creator | Vázquez Tato, María del Pilar | |
| dc.creator | Granados Zúñiga, Jorge | |
| dc.creator | Alvarado, María José | |
| dc.creator | Somarribas Patterson, Luis Felipe | |
| dc.creator | Seijas, Julio A. | |
| dc.creator | Soto Tellini, Victor Hugo | |
| dc.date.accessioned | 2019-06-17T20:00:31Z | |
| dc.date.available | 2019-06-17T20:00:31Z | |
| dc.date.issued | 2019-01 | |
| dc.description.abstract | Two ether and one ester derivatives of the 4-nitro-3-hydroxybenzoic acid were synthesized and characterized. The in vitro antimicrobial and cytotoxic activities of the three novel compounds were also evaluated. The aromatic derivatives showed antibacterial activity against one of the four microorganisms tested and two compounds (C8 and NOBA) had a lower IC50 in HeLa cells. | es |
| dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA) | es |
| dc.description.procedence | UCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de Química | es |
| dc.description.procedence | UCR::Vicerrectoría de Docencia::Salud::Facultad de Medicina::Escuela de Medicina | es |
| dc.description.sponsorship | Ministerio de Ciencia y Tecnología/[MAT2013-45657-P]/MICITT/Costa Rica | es |
| dc.identifier.citation | http://www.eurekaselect.com/166552/article | |
| dc.identifier.codproyecto | 742-B6271 | |
| dc.identifier.doi | https://doi.org/10.2174/1570178615666181023151308 | |
| dc.identifier.issn | 1875-6255 | |
| dc.identifier.uri | https://hdl.handle.net/10669/77443 | |
| dc.language.iso | en_US | |
| dc.rights | acceso abierto | |
| dc.rights.uri | http://creativecommons.org/publicdomain/zero/1.0/ | |
| dc.source | Letters in Organic Chemistry, vol.16, pp. 1-7. | es |
| dc.subject | Cytotoxic activity | es |
| dc.subject | Antimicrobial activity | es |
| dc.subject | Aromatic | es |
| dc.subject | 4-nitro-3-hidroxybenzoic acid | es |
| dc.subject | Surfactants | es |
| dc.subject | Organic chemistry | es |
| dc.subject | 547 Química orgánica | es |
| dc.title | Synthesis and Evaluation of Aromatic Surfactants as Potential Antibacterial and Cytotoxic Agents | es |
| dc.type | artículo original |