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Redox stress reshapes carbon fluxes of Pseudomonas putida for cytosolic glucose oxidation and NADPH generation
(2020)
The soil bacterium and metabolic engineering platform Pseudomonas putida tolerates high levels of endogenous and exogenous oxidative stress, yet the ultimate reason of such property remains unknown. To shed light on this ...
Degree of intervention affects interannual and within-plot heterogeneity of seed arrival in tropical forest restoration
(2021-05-11)
In degraded tropical landscapes, lack of seed dispersal can strongly limit recovery, and restoration interventions can overcome this barrier by attracting dispersers. However, seed dispersal patterns are typically studied ...
In vitro studies to evaluate the wound healing properties of Calendula officinalis extracts
(2017)
Ethnopharmacological relevance: Calendula officinalis (pot marigold) flower extracts have a long-lasting tradition in ethnopharmacology. Currently, the European Medicines Agency (EMA) has approved its lipophilic and aqueous ...
Current approaches to the isolation and structural elucidation of active compounds from natural products
(2018)
The essence of medicinal plants, either as pure compounds or as standardized extracts, provides unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to an increasing ...
Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis
(2015)
Oral squamous cell carcinoma (OSCC) is the most common cancer affecting the oral cavity, and US clinics will register about 30,000 new patients in 2015. Current treatment modalities include chemotherapy, surgery, and ...
Alkaloids from Crinum erubescens Aiton
(2016-09)
Eight alkaloids have been identified from fresh leaves of Crinum erubescens (Amaryllidaceae) collected in Costa Rica. The alkaloid 1-epidemethylbowdensine, detected by means of GC–MS as part of a global Amaryllidaceae ...
From dirt to industrial applications: Pseudomonas putida as a Synthetic Biology chassis for hosting harsh biochemical reactions
(2016-10)
The soil bacterium Pseudomonas putida is endowed with a central carbon metabolic network capable of fulfilling high demands of reducing power. This situation arises from a unique metabolic architecture that encompasses the ...
Interplay of the PtsN (EIIANtr) protein of Pseudomonas putida with its target sensor kinase KdpD
(2015-08-27)
The nitrogen phosphotransferase system (PTSNtr) of Pseudomonas putida is a multi-component regulatory device that participates in controlling a variety of physiological processes in a post-translational fashion. A general ...
Maternal health in Central America: The role of medicinal plants in the pregnancy-related health and well-being of indigenous women in Central America
(2018)
Over the past 20 years, Central America (CA) has made considerable progress in improving the health status of its populations. However, in some countries, the overall health status remains below average with poor outcomes ...
Composition of the essential oil from leaves of Smallanthus quichensis (Asteraceae) from Costa Rica
Composición química del aceite esencial de las hojas de Smallanthus quichensis (Asteraceae) de Costa Rica
(2015-09-30)
Smallanthus is a genus of flowering plants in the Asteraceae family, which has about 24 species, ranging mostly from southern Mexico and Central America to the Andes in South America. The aim of the present study was to ...