Biología
Envíos recientes
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Hallazgos fenotípicos por imágenes con Tomografía Dental Volumétrica (TDV) en amelogénesis imperfecta
(2016)Amelogénesis imperfecta (AI) se describe como un conjunto de defectos mendelianos en la biomineralización del esmalte dental, los cuales son severos en la mayoría de los casos al presentar anormalidades tales como un grosor ... -
Genome Sequencing of Sulfolobus sp. A20 from Costa Rica and Comparative Analyses of the Putative Pathways of Carbon, Nitrogen, and Sulfur Metabolism in Various Sulfolobus Strains
(2016-11-30)The genome of Sulfolobus sp. A20 isolated from a hot spring in Costa Rica was sequenced. This circular genome of the strain is 2,688,317 bp in size and 34.8% in G+C content, and contains 2591 open reading frames (ORFs). ... -
Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis
(2016-06-16)Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still ... -
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats
(2016-07-12)Transcript variation has important implications for organismal function in health and disease. Most transcriptome studies focus on assessing variation in gene expression levels and isoform representation. Variation at the ... -
A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y
(2016-02)The mammalian Y Chromosome sequence, critical for studying male fertility and dispersal, is enriched in repeats and palindromes, and thus, is the most difficult component of the genome to assemble. Previously, expensive ... -
Salivary gland morphology, tissue tropism and the progression of tospovirus infection in Frankliniella occidentalis
(2016)Tomato spotted wilt virus (TSWV) is transmitted by thrips in a propagative manner; however, progression of virus infection in the insect is not fully understood. The goal of this work was to study the morphology and infection ... -
Phylogenetic reassessment of Specklinia and its allied genera in the pleurothallidinae (Orchidaceae)
(2016)The phylogenetic relationships within Specklinia (Pleurothallidinae; Orchidaceae) and related genera are re-evaluated using Bayesian analyses of nrITS and chloroplast matK sequence data of a wide sampling of species. ... -
Sobre el genoma humano, la medicina personalizada y el sistema de seguridad social
(2016)La promesa del proyecto del genoma humano (PGH) fue que iba a transformar radicalmente la práctica médica. Cambiaría el paradigma de “diagnóstico y tratamiento” por el de “predicción de riesgo y prevención”. Hace más de ... -
Neuropsychological Test Performance in Cognitively Normal Spanish-speaking Nonagenarians with Little Education
(2016-06)To find associations of age, sex, and education with neuropsychological test performance in cognitively normal Spanish-speaking Costa Rican nonagenarians with little education; to provide norms; and to compare their ... -
Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder
(2016-02-09)Abnormalities in sleep and circadian rhythms are central features of bipolar disorder (BP), often persisting between episodes. We report here, to our knowledge, the first systematic analysis of circadian rhythm activity ... -
Genetic diversity in Oryza glumaepatula wild rice populations in Costa Rica and possible gene flow from O. sativa
(2016-04-07)Wild crop relatives are an important source of genetic diversity for crop improvement. Diversity estimates are generally lacking for many wild crop relatives. The objective of the present study was to analyze how genetic ... -
Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder
(2016-05-13)The observation that variants regulating gene expression (expression quantitative trait loci, eQTL) are at a high frequency among SNPs associated with complex traits has made the genome-wide characterization of gene ... -
A microbial consortium from a biomixture swiftly degrades high concentrations of carbofuran in fluidized-bed reactors
(2016)An on-farm biopurification system (BPS) biomixture, with proven capacity to degrade carbofuran (CBF) was used as inoculum for a selective-enrichment process to obtain a bacterial consortium capable of using CBF as a sole ... -
Molecular characterization and genetic diversity of Jatropha curcas L. in Costa Rica
(2017-02-09)We estimated the genetic diversity of 50 Jatropha curcas samples from the Costa Rican germplasm bank using 18 EST-SSR, one G-SSR and nrDNA-ITS markers. We also evaluated the phylogenetic relationships among samples using ... -
Cellulose-Enriched Microbial Communities from Leaf-Cutter Ant (Atta colombica) Refuse Dumps Vary in Taxonomic Composition and Degradation Ability
(2016-03-21)Deconstruction of the cellulose in plant cell walls is critical for carbon flow through ecosystems and for the production of sustainable cellulosic biofuels. Our understanding of cellulose deconstruction is largely limited ... -
Selvamicin, an atypical antifungal polyene from two alternative genomic contexts
(2016-11-15)The bacteria harbored by fungus-growing ants produce a variety of small molecules that help maintain a complex multilateral symbiosis. In a survey of antifungal compounds from these bacteria, we discovered selvamicin, an ... -
Deletion of amelotin exons 3–6 is associated with amelogenesis imperfecta
(2016-07-12)Amelogenesis imperfecta (AI) is a heterogeneous group of genetic conditions that result in defective dental enamel formation. Amelotin (AMTN) is a secreted protein thought to act as a promoter of matrix mineralization in ... -
In favor of establishment: chromatid cohesion in plants
(2017-05-23)In eukaryotic organisms, the correct regulation of sister chromatid cohesion, whereby sister chromatids are paired and held together, is essential for accurate segregation of the sister chromatids and homologous chromosomes ... -
Descripción de experiencias para el mejoramiento de la enseñanza de las ciencias
(1989-09-07)El documento incluye dos trabajos. En el primero se exponen las acciones de educación no formal en la enseñanza de las ciencias que han beneficiado a docentes de niveles pre-universitarios del Sistema Educativo Nacional ...
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