Quality control performed on liposomal formulations based on guarana extract, vitamins a, c, e, b1, b2, b5, b6, b12, biotin and folic acid, used as nutritional products




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Madrigal Redondo, German
Vargas Zúñiga, Rolando
Chavarría Rojas, Marianela
Sibaja Rodríguez, Santiago
Chaves Noguera, Sindy

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The study of has increased in the last decades. One of the mechanisms that has acquired great relevance is to formulate using liposomal vesicles. Liposomes are structures that enh and transport of active compounds, which is reflected by an increase in the bioactivity of the encapsulated molecules. The guarana extract has proven to be rich in methylxanthines and phenolic compounds. These metabolites are exert a stimulating effect. For this reason, it has become popular in nutritional products. was characterized physicochemically a nutritional product based on guarana, vitamins In this product the active components were encapsulated in liposomal vesicles, which were analyzed to know their structure, size (diameter) and membrane thickness. liposomes are multivesicular and multilam greater stability of the vesicles, which represents a favorable aspect for the formulation. hand, the data obtained from the physicochemical characterization can be used as part of control performed on the formulation. Additionally, they represent a starting point for improvements and optimization of this nutritional product. Copyright©2017, Madrigal-Redondo et al. This is an open access article distributed under the use, distribution, and reproduction in any medium, provided the original work is properly cited


Palabras clave

Phosphatidylcholine, Multivesicular Liposomes, Multilamellar Liposomes, Paullinia cupana, Nutritional product.