Cáncer de mama en mujeres jóvenes. Características clínicas y patológicas.
Date
Authors
Quirós Alpízar, José Luis
Arce Jiménez, Isabel Cristina
Ramírez, Benjamín
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Volume Title
Publisher
Revista Médica de la Universidad de Costa Rica. Volumen 4, número 2, artículo 7.
Abstract
El presente estudio tiene como objetivo caracterizar los carcinomas invasores de la
glándula mamaria de una cohorte de 72 mujeres menores de 50 años, diagnosticadas
durante el año 2006 en un centro de salud capitalino de atención terciaria en Costa
Rica. Se investigaron los marcadores biológicos: edad, tipo histológico, receptores
hormonales [RE, RP y HER2], grado histológico, diámetro y estadio de los ganglios
axilares. Se encontró una predominancia de carcinomas del tipo ductal infiltrante
(84,85%, n=56), de grado histológico alto (86,00% n=43), con tamaño mayor o igual a
los 2cm (73,21% n=41), estadio de ganglios negativos (59,09% n=26) y de subtipo
inmunohistoquímico Luminal A (48,61% n=35). Entre otros hallazgos, se encontró una
frecuencia del 22,22% (n=16) de carcinomas triple negativos, de 7,57% (n=5) del tipo
histológico lobulillar y 4,45% (n=3) del tipo medular.
Abstract: The aim of this study is to characterize breast invasive carcinomas in a cohort of 72 women under 50 years of age diagnosed through 2006 in a tertiary health care facility in Costa Rica. We analyzed biological biomarkers: age, histological type, hormone receptors [ER, PR and HER2], histological grade, tumor diameter and axillary lymph node status. There was identified a higher prevalence of invasive ductal carcinoma (84,85%, n=56), high histological grade (86,00% n=43), tumor diameter larger than 2cm (74% n=41), lymph node negative status (59,09% n=26) and Luminal A inmunohistochemical subtype (48,61% n=35). In addition, results demonstrate high frequency of triple negative carcinomas (22,22% n=16), invasive lobular (7,57% n=5) and medullary (4,45% n=3) histological type.
Abstract: The aim of this study is to characterize breast invasive carcinomas in a cohort of 72 women under 50 years of age diagnosed through 2006 in a tertiary health care facility in Costa Rica. We analyzed biological biomarkers: age, histological type, hormone receptors [ER, PR and HER2], histological grade, tumor diameter and axillary lymph node status. There was identified a higher prevalence of invasive ductal carcinoma (84,85%, n=56), high histological grade (86,00% n=43), tumor diameter larger than 2cm (74% n=41), lymph node negative status (59,09% n=26) and Luminal A inmunohistochemical subtype (48,61% n=35). In addition, results demonstrate high frequency of triple negative carcinomas (22,22% n=16), invasive lobular (7,57% n=5) and medullary (4,45% n=3) histological type.
Description
Keywords
Receptor de Progesterona, Cáncer, Grupo de edad, Inmunohistoquímica, Receptores Estrogénicos
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