Efectos de la irradiación neutrónica del Uranio 235 sobre el veneno de Lachesis muta muta (Ofidia: Viperidae)
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Authors
Becerra, Paúl
Zavaleta Martínez Vargas, Alfonso
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Universidad de Costa Rica
Abstract
Description
The effect of irradiation of the aqueous solution of L. m. mula venom was evaluated with thennic neulrons from Uranium-235 employing doses of 1.61to 5.19 Gray. The venom was examined for protein content by the Folín Lowry Method modified by Stauffer; for acute toxicity by intraperitoneal route estimation in mice and for Írnmunochemical tests by the anti gen-antibody reactions evaluation. Neutronic radiation affects ail evaluated parameters in venom (decrease in protein content levels, increase oí LD50 values and decrease in the number of precipitating antigen-antibody) as shown by immunodiffusion and immunoelectropboresis