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Uses and misuses of definitions of genetic polymorphism: A perspective from population pharmacogenetics

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Authors

Arias, Tomas D.
Jorge, L. F.
Barrantes Mesén, Ramiro

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Abstract

Definitions of genetic polymorphism currently employed in the pharmacological literature have been incorrectly used (Kalow, 1984) and uncritically imported from population genetics [e.g., Weinshilboum (1984), Evans (1977)], apparently without regard to the problems their application might present in pharmacogenetics or, more specifically, in pharmacogenetic studies of populations.

Description

carta al editor -- Universidad de Costa Rica. Instituto de Investigaciones en Salud. 1991

Keywords

farmacogenesis, polimorfismo, Genética humana, Genética

Citation

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1991.tb03870.x/abstract

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