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Diagnosis of Schizophrenia in Latino Populations. A Comparison of Direct Interview and Consensus Based Multi-Source Methods
(Journal of Nervous and Mental Disease 2009;197: 530–535, 2009-07)
We determined the rates of agreement between diagnoses, using
the Diagnostic Interview for Genetic Studies (DIGS) and diagnoses arrived
at, using additional sources of information, to establish whether there are
differences ...
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
(Human Biology, October 2006, v. 78, no. 5, pp. 551–563., 2006)
Two hundred seventeen male subjects from Costa Rica, Mexico,
and the Hispanic population of the southwestern United States were
studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA
were analyzed to ...
Substance use disorder and schizophrenia: prevalence and sociodemographic characteristics in the Latin American population
Esquizofrenia y trastorno en el consumo de sustancias: prevalencia y características sociodemográficas en la población Latina
(Actas Esp Psiquiatr 2011;39(2):123-30, 2011)
El interés por comprender la co-morbilidad de la esquizofrenia
y el trastorno en el uso de sustancias, ha aumentado
debido al incremento de este diagnóstico, a los
efectos negativos observados en el sujeto y a los ...
Adjudicating Neurocognitive Endophenotypes for Schizophrenia
(American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 144B:242–249 (2007), 2007-03-05)
Although genetic influences on schizophrenia
are well established, localization of the genes
responsible for this illness has proven extremely
difficult. Given evidence that genes predisposing
to schizophrenia may be ...
Caracterización de un grupo de pacientes con esquizofrenia en el Valle Central de Costa Rica
(AMC, vol 50 (3), julio-setiembre 2008, 2008)
La esquizofrenia es una enfermedad crónica con importantes
repercusiones sociales que afecta al 1% de la población mundial. Se describe las características de la esquizofrenia en una muestra de pacientes del Valle Central ...
Neurocognitive endophenotypes for bipolar disorder identified in multiplex multigenerational families
(Arch Gen Psychiatry. 2010;67(2):168-177, 2010-02-01)
Context: Although genetic influences on bipolar disorder
are well established, localization of genes that predispose
to the illness has proven difficult. Given that genes
predisposing to bipolar disorder may be transmitted ...
Shared Genetic Factors Influence Risk for Bipolar Disorder and Alcoholism
(2014-06)
Bipolar disorder and alcoholism have high rate comorbidity, with more than 50% of alcoholism
occurrence in bipolar disorder. While there is evidence that both disorders are heritable, it is unclear
if the same genetic ...
Genetic structure of personality factors and bipolar disorder in families segregating bipolar disorder
(Journal of Affective Disorders xxx (2011) xxx–xxx, 2011)
Bipolar disorder (BPD) has been associated with variations in personality dimensions,
but the nature of this relationship has been unclear. Inthis study, theheritabilities of BPDandtheBig
Five personality factors and the ...
A schizophrenia gene locus on chromosome 17q21 in a new set of families of mexican and central american ancestry: evidence from the NIMH genetics of schizophrenia in latino populations study
(Am J Psychiatry 2009;166:442-449, 2009-02-02)
The present study investigated a new set of families of Latin American ancestry in order to detect the location of genes predisposing to schizophrenia and related psychotic disorders. Method: A genome-wide scan was performed ...
In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation
(J Mol Med (Berl). 2010 November ; 88(11): 1133–1141, 2010-11)
Neuregulin 1 (NRG1) has been implicated in several disorders including breast cancer, multiple sclerosis, and schizophrenia. Also, recent evidence suggests that NRG1 may play a role in regulation of inflammation and immune ...