Listar Medicina, ciencias biomédicas y salud pública por autor "2dc86390-cca9-4aaa-b286-1bf635cdcc5a"
Mostrando ítems 1-12 de 12
-
Cromosomopatías en pacientes con cáncer sometidos a radioterapia con cobalto 60
Fernández Barrero, Claudia; Ramírez Mayorga, Vanessa; Mora Rodríguez, Patricia; Recinos Pineda, Hugo; Rodríguez González, Marvin; García Lima, Omar; Rodríguez Alvarado, Silvia; Malespín Bendaña, Wendy Karina; Valle Bourrouet, Luisa María (2022-10-13)Aim: The objective of this study was to describe the before and after cytogenetic aberrations found in current patients of radiotherapy. This can be observed through the technique called “Giemsa in ... -
Diagnóstico molecular de cromosomopatías fetales en Costa Rica
Malespín Bendaña, Wendy Karina; Ortiz Morales, Fernando; Castro Volio, Isabel (Acta méd. costarric. Vol 51 (5), octubre-diciembre 2009 p.240-244, 2009-10)Justificación y objetivos: En Costa Rica, el diagnóstico de anomalías cromosómicas fetales se realiza solo mediante el análisis citogenético convencional de cromosomas obtenidos de cultivos celulares. Además de que la ... -
Helicobacter pylori infection and serum pepsinogen concentrations in an elderly population representative of Costa Rica
Une, Clas Allan; Malespín Bendaña, Wendy Karina; Ramírez Mayorga, Vanessa; Rosero Bixby, Luis; Sierra Ramos, Rafaela (2022)INTRODUCTION: Costa Rica has among the highest mortality rates from gastric cancer in the world, largely due to late detection. It is therefore important that economically and logistically sustainable screening is implemented ... -
Helicobacter pylori infection induces gastric precancerous lesions and persistent expression of Angpt2, Vegf-A and Tnf-A in a mouse model
Malespín Bendaña, Wendy Karina; Alpízar Alpízar, Warner; Figueroa Protti, Lucía; Reyes Moreno, Ledis; Molina Castro, Silvia Elena; Une, Clas Allan; Ramírez Mayorga, Vanessa (2023)Helicobacter pylori colonizes the gastric mucosa and induces chronic inflammation. Using a mouse model of H. pylori-induced gastritis, we evaluated the mRNA and protein expression levels of proinflammatory and proangiogenic ... -
Helicobacter pylori infection induces abnormal expression of pro‑angiogenic gene ANGPT2 and miR‑203a in AGS gastric cell line
Malespín Bendaña, Wendy Karina; Ferreira, Rui M.; Pinto, Marta T.; Figueiredo, Ceu; Alpízar Alpízar, Warner; Une, Clas Allan; Figueroa Protti, Lucía; Ramírez Mayorga, Vanessa (2023-03-06)Helicobacter pylori colonizes the stomach and induces an inflammatory response that can develop into gastric pathologies including cancer. The infection can alter the gastric vasculature by the deregulation of angiogenic ... -
Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori
Alpízar Alpízar, Warner; Didrik Laerum, Ole; Illemann, Martin; Ramírez Corrales, José Alberto; Arias, Adriana; Malespín Bendaña, Wendy Karina; Ramírez Mayorga, Vanessa; Lund, Leif R.; Borregaard, Niels; Schnack Nielsen, Boye (2009-09)Helicobacter pylori infection is one of the most significant risk factors for gastric cancer. The infection is established early in life and persists lifelong leading to a sustained chronic inflammation. Iron is essential ... -
Polymorphisms in Genes Coding for HSP-70 Are Associated with Gastric Cancer and Duodenal Ulcer in a Population at High Risk of Gastric Cancer in Costa Rica
Ferrera Ferrera, Maura; Malespín Bendaña, Wendy Karina; Ramírez Mayorga, Vanessa; González Lutz, María Isabel; Carvajal, Adriana; Une, Clas Allan (2013)Background and Aims. Costa Rica has among the highest incidence and mortality rates for gastric cancer worldwide. The reasons for this are largely unknown. Polymorphisms of inflammatory response genes including genes ... -
Prenatal diagnosis of i(18q) and dup(18q) cases by quantitative fluorescent PCR
Castro Volio, Isabel; Ortiz Morales, Fernando; Valle Bourrouet, Luisa María; Malespín Bendaña, Wendy Karina (2013-09)Particular sonographic fetal malformations are common in chromosome 18 aberrations, requiring invasive prenatal tests to confirm the diagnosis. Karyotyping is the gold standard assay in these cases, although it is a high ... -
The geographic origin of Helicobacter pylori isolated from Costa Rican patients
Molina Castro, Silvia Elena; Herrera Ríos, Dayana; Malespín Bendaña, Wendy Karina; Ramírez Mayorga, Vanessa; Une, Clas Allan (2014-07)Helicobacter pylori infects a significant proportion of the world population and it is associated with pathologies which include chronic atrophic gastritis, peptic ulcer, and gastric neoplasias such as gastric adenocarcinoma ... -
The TNF-A–857*T polymorphism is associated with gastric adenocarcinoma risk in a Costa Rican population
Malespín Bendaña, Wendy Karina; Machado, José Carlos; Une, Clas Allan; Alpízar Alpízar, Warner; Molina Castro, Silvia Elena; Ramírez Mayorga, Vanessa (2021-01)Background: Costa Rica is ranked as one of the countries with highest incidence of gastric cancer worldwide. Previous studies in Costa Rican populations have revealed associations between gastric cancer risk and several ... -
Validación de una prueba serológica para detectar la infección por Helicobacter pylori en Costa Rica
Méndez Chacón, Ericka; Ramírez Mayorga, Vanessa; Malespín Bendaña, Wendy Karina; Pérez Pérez, Guillermo Ignacio; Une, Clas Allan (2020)Helicobacter pylori es una bacteria Gram negativa capaz de sobrevivir y multiplicarse en la mucosa gástrica humana. Es el factor más importante en el desarrollo de gastritis atrófica crónica, ... -
Virulence factor genotyping of Helicobacter pylori isolated from Costa Rican dyspeptic patients
Molina Castro, Silvia Elena; Garita Cambronero, Jerson; Malespín Bendaña, Wendy Karina; Une, Clas Allan; Ramírez Mayorga, Vanessa (2019-01-14)Background and aims: Costa Rica is one of the countries with the highest incidence and mortality rates for gastric cancer. Helicobacter pylori infection rates are high in the whole country. We have previously shown that ...