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Situación actual de la Leucemia Aguda de Linaje Ambiguo: Una revisión sistemática
(2021-08)
La leucemia aguda es un cáncer hematopoyético en la cual prolifera una población de células malignas llamadas blastos, que comprometen más del 20% del componente celular de la médula ósea. La gran mayoría de estas pueden ...
Identification of cancer chemosensitivity by ODE and GMM modeling of heterogeneous cellular response to perturbations in fluorescent sphingolipid metabolism
(2016-11-11)
Cancer refers to a group of diseases in which cells display uncontrolled growth. Chemotherapy options are usually conditioned by generating resistance which is explained in part by the intrinsic heterogeneity of the ...
Group-II phospholipase A2 enzymes
(2015-05)
Phospholipase A2 are esterolytic enzymes that catalyze the hydrolysis of 1,2-diacyl-3-sn-glycerophospholipids at the C2 position, resulting in the formation of lysophospholipids and free fatty acid. They constitute one of ...
Shigellosis in Central America
(Shigellosis: a continuing global problem:ICDDR,Bangladesh p 26-38, 1983)
Shigella infections are very common in Central America, except in Costa
Rica and Panama where prevalence rates are low. Shigellosis is the most
serious among all the specific diarrhoeas, due to its invasive character,
systemic ...
A lipidomic perspective of the action of group IIA secreted phospholipase A2 on human monocytes: lipid droplet biogenesis and activation of cytosolic phospholipase A2α
(2020)
Phospholipase A2s constitute a wide group of lipid-modifying enzymes which display a variety of functions in innate immune responses. In this work, we utilized mass spectrometry-based lipidomic approaches to investigate ...
An acidic phospholipase A2 with antibacterial activity from Porthidium nasutum snake venom
(2012-04)
Snake venoms are complex mixtures of proteins among which both basic and acidic phospholipases A2
(PLA2s) can be found. Basic PLA2s are usually responsible for major toxic effects induced by snake venoms,
while acidic ...
Bacterial Sphingomyelinases and Phospholipases as Virulence Factors
(2016-06-15)
Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze ...
Virus del Epstein-Barr y su relacion con el desarrollo de sindromes linfoproliferativos, especificamente el linfoma de Hodgkin, el linfoma de Burkitt y los desordenes linfoproliferativos postrasplante
(2021-08-03)
El virus del Epstein-Barr (EBV) es un herpes humano 4 extendido por toda la población mundial y se transmite como una infección asintomática latente en la gran mayoría de las personas. Sin embargo, este mismo virus es un ...
Proteomic analysis of the mandibular glands from the Chinese crocodile lizard, Shinisaurus crocodilurus – another venomous lizard?
(2023)
Based on its phylogenetic relationship to monitor lizards (Varanidae), Gila monsters (Heloderma spp.), and the earless monitor Lanthanotus borneesis, the Chinese crocodile lizard, Shinisaurus crocodilurus, has been assigned ...