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Ability of a polyvalent antivenom to neutralize the venom of Lachesis muta melanocephala, a new Costa Rican subspecies of the bushmaster
(1987)
Several toxic and enzymatic activities of the venom of L. m. melanocephala were studied. This venom has many similarities with that of L. m. stenophrys, although there are quantitative differences in venom activities, as ...
Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis)
(2017-01)
Bothriechis is a genus of eleven currently recognized slender and arboreal venomous snakes, commonly called
palm-pitvipers that range from southern Mexico to northern South America. Despite dietary studies suggesting
that ...
Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective?
(2010-01)
The study of snake venom-induced local tissue pathology has been predominantly based on experimental designs and concepts that view tissue alterations from a dichotomous, homogeneous and reductionist perspective. Experimental ...
12-HETE is a regulator of PGE2 production via COX-2 expression induced by a snake venom group IIA phospholipase A2 in isolated peritoneal macrophages
(2020)
The snake venom myotoxin (MT)-III is a group IIA secreted phospholipase A2 (sPLA2) with pro-inflammatory activities. Previous studies have demonstrated that MT-III has the ability to stimulate macrophages to release ...
Toxicovenomics and antivenom profiling of the Eastern green mamba snake (Dendroaspis angusticeps).
(2016-03-16)
A toxicovenomic study was performed on the venom of the green mamba, Dendroaspis angusticeps. Forty-two different proteins were identified in the venom of D. angusticeps, in addition to the nucleoside adenosine. The most ...
Evaluation of antivenoms in the neutralization of hyperalgesia and edema induced by Bothrops jararaca and Bothrops asper snake venoms
(2002-10)
Neutralization of hyperalgesia induced by Bothrops jararaca and B. asper venoms was studied in rats using bothropic antivenom produced at Instituto Butantan (AVIB, 1 ml neutralizes 5 mg B. jararaca venom) and polyvalent ...
Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding
(2016-03-26)
The historical development of discoveries and conceptual frames for understanding the hemorrhagic activity induced by viperid snake venoms and by hemorrhagic metalloproteinases (SVMPs) present in these venoms is reviewed. ...
Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity
(2006-05)
Several snake venom secreted phospholipases A2 (sPLA2s) including OS2 exert a variety of pharmacological effects ranging from central neurotoxicity to anti-HIV activity by mechanisms that are not yet fully understood. To ...
Comparative study on the ability of IgG and F(ab')2 antivenoms to neutralize lethal and myotoxic effects induced by Micrurus nigrocinctus (coral snake) venom
(1999-08)
A comparative study was performed on the ability of IgG and F(ab')2 antivenoms to neutralize lethal and myotoxic activities of Micrurus nigrocinctus venom. Both antivenoms were adjusted to a similar neutralizing potency ...
Physicochemical characterization of Jicaro seeds (Crescentia alata H.B.K.): a novel protein-rich and oleaginous seed
(2017-03)
Jicaro (Crescentia alata) is a tropical tree native to Mesoamerica well adapted to severe drought
conditions. The seeds of the fruits were analyzed for protein, fatty acid, dietary
fiber, phytate, polyphenol,
tannin, ...