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Mostrando ítems 391-400 de 445
Envenamiento por mordedura de serpiente en Costa Rica en 1996: Epidemiología y consideraciones clínicas
(1999-12)
El presente trabajo se efectúa para tener una visión actualizada y completa de las principales características epidemiológicas del envenenamiento por mordedura de serpiente en Costa Rica. Asimismo, se incluyen algunas ...
Dr. Clodomiro Picado Twight (1887-1944)
(2010)
Semblanza de Clodomiro Picado Twight, quien jugó un papel central en el desarrollo inicial de varias ramas de la ciencia en Costa Rica. Su formación académica se inició en el Colegio San Luis Gonzaga, en Cartago, donde ...
Estudio comparativo de los venenos de serpiente Cascabel (Crotalus durissus durissus) de ejemplares adultos y recien nacidos
Comparative study of venoms of newborn and adult rattlesnakes (Crotalus durissus durissus)
(1983)
Venoms from adult and newborn Central American rattlesnakes (Crotalus durissus durissus) were compared for lethal, proteolytic, hemorrhagic, myonecrotic, edematigenous and in vitro hemolytic activities. Electrophoretic and ...
Histopathological and biochemical alterations induced by intramuscular injection of Bothrops asper (terciopelo) venom in mice
(1989)
The local and systemic pathological changes induced by an i.m. injection of 100 micrograms of Bothrops asper venom in mice were studied histologically and by following the changes in serum levels of enzymes, proteins, ATP ...
Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: identification of key toxin targets for antivenom development.
(2015-04-24)
The venom proteome of the black mamba, Dendroaspis polylepis, from Eastern Africa, was, for the first time, characterized. Forty- different proteins and one nucleoside were identified or assigned to protein families. The ...
Costa rican international cooperative biodiversity group: using insects and other arthropods in biodiversity prospecting
In: J. Rosenthal (Ed.). Drug discovery, economic development and conservation: The International Cooperative Biodiversity Groups. Pharm. Biol. Vol 37, Supplement, pp. 55-68.
(Pharmaceutical Biology 37(Supplement):55–68. 1999, 1999)
This paper describes the Costa Rican International Collaborative Biodiversity Group (ICBG), which was designed to introduce insects and other arthropods as a source of pharmaceutical compounds, and to generate knowledge ...
Antibody-mediated neutralization and binding-reversal studies on α-neurotoxins from micrurus nigrocinctus nigrocinctus (coral snake) venom
(1996-03)
An ELISA based, non-radioactive acetylcholine receptor (AchR) binding assay was used to detect the alpha-neurotoxins present in Micrurus nigrocinctus nigrocinctus venom. Sera from horses hyperimmunized against M. nigrocinctus ...
Isolation and characterization of synergistic hemorrhagins from the venom of the snake Bothrops asper
(1993-09)
Three hemorrhagic factors (BaH1, BH2 and BH3) were isolated from the venom of Bothrops asper by gel filtration on Sephacryl S-200, DEAE-Sepharose chromatography, metal chelate affinity chromatography and hydrophobic ...
Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa
(2005-06)
A polyspecific Pan-African antivenom has been produced from the plasma of horses immunized with a mixture of the venoms of Echis ocellatus, Bitis arietans and Naja nigricollis, the three most medically important snakes in ...
Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
(2014-09-01)
Snakebite envenoming constitutes an important public health problem in Latin America and some countries of
the Caribbean. The advances and pending tasks in the study and control of this neglected tropical disease in ...