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The analgesics morphine and tramadol do not alter the acute toxicity induced by Bothrops asper snake venom in mice

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Gutiérrez, José María
Herrera Arias, Cristina

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Abstract

Analgesics tramadol and morphine were used in mice injected with Bothrops asper venom. Analgesics did not alter the acute toxicity of B. asper venom in mice. Precautionary (prophylactic) analgesia should be introduced routinely in Toxinology.

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Keywords

Analgesics, Animal Welfare, Animals, Bothrops, Crotalid Venoms, Edema, Hemorrhage, Mice, Inbred Strains, Morphine, Pain, Snake Bites, Toxicity Tests, Acute, Tramadol

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