Emergence of Clostridium difficile NAP1 in Latin America
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Authors
Quesada Gómez, Carlos
Rodríguez Sánchez, César
Gamboa Coronado, María del Mar
Rodríguez Cavallini, Evelyn
Du, Tim
Mulvey, Michael R.
Villalobos Zúñiga, Manuel Antonio
Boza Cordero, Ricardo
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Abstract
The NAP1 and NAP2 strains of Clostridium difficile have been linked to nosocomial outbreaks of antibiotic-associated diarrhea (AAD) and pseudomembranous colitis in North American and European countries (4, 5). We found these strains, together with seven additional pulsed-field gel electrophoresis (PFGE) patterns, among 37 isolates recently recovered from patients with AAD in a Costa Rican hospital. Herein we present the macrorestriction patterns of the isolates as well as data regarding their toxin genotypes and susceptibility to selected antibiotics.
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Keywords
Clostridium difficile, América Latina, 589.958 Clostridium