Current approaches to the isolation and structural elucidation of active compounds from natural products

Abstract

The essence of medicinal plants, either as pure compounds or as standardized extracts, provides unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to an increasing demand for chemical diversity in screening programs, seeking therapeutic drugs from natural products, the isolation of compounds from edible plants has grown. Botanicals and herbal preparations for medicinal usage contain various types of bioactive compounds. The focus of this chapter is on revised current analytical methodologies, which include the extraction, isolation, and identification of bioactive principles in natural products. Chromatographic techniques such as LC and spectroscopic methods like NMR and MS will be discussed.