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An alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Rica

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dc.creatorGutiérrez, José María
dc.creatorÁvila Agüero, Claudio
dc.creatorCerdas Fallas, Luis
dc.creatorRojas Umaña, Ermila
dc.creatorCerdas Fallas, Luis
dc.date.accessioned2016-11-07T16:16:36Z
dc.date.available2016-11-07T16:16:36Z
dc.date.issued1988
dc.description.abstractThe ability of several batches of polyvalent antivenom to neutralize indirect hemolytic activity of Bothrops asper venom was studied using a sensitive plate test. All samples of antivenom tested effectively neutralized this activity. A highly significant correlation was observed between neutralization of indirect hemolysis and neutralization of lethal activity. This simple and sensitive in vitro test could be used to monitor antibody levels in horses immunized to produce polyvalent antivenom.es
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/0041010188900104
dc.identifier.doihttps://doi.org/10.1016/0041-0101(88)90010-4
dc.identifier.issn0041-0101
dc.identifier.urihttps://hdl.handle.net/10669/29152
dc.language.isoen_US
dc.rightsacceso embargado
dc.sourceToxicon; Volumen 26, Número 4, 1988es
dc.subjectAnimalses
dc.subjectAntiveninses
dc.subjectCosta Ricaes
dc.subjectCrotalid Venomses
dc.subjectHemolysises
dc.subjectDrug Effectses
dc.subjectHorseses
dc.subjectImmunologyes
dc.subjectIn Vitro Techniqueses
dc.subjectMicees
dc.subjectNeutralization Testses
dc.subjectSnake venomes
dc.titleAn alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Ricaes
dc.typeartículo original

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