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Synthesis and Antibacterial Activity of Aromatic Homopropargyl Alcohols

dc.creatorUmaña, Christian A.
dc.creatorArias Echandi, María Laura
dc.creatorCabezas Pizarro, Jorge A.
dc.date.accessioned2023-01-03T16:38:56Z
dc.date.available2023-01-03T16:38:56Z
dc.date.issued2017
dc.description.abstractSeveral aromatic homopropargyl alcohols, and derivatives were prepared by one-pot reaction of 1,3-dilithiopropyne (or its equivalent) with aldehydes and ketones. The antibacterial activity, of alcohols thus prepared, against Gram (+) and Gram (−) bacteria was tested. This activity varies depending upon substitution on the homopropargyl alcohol unit. Apparently, the benzene ring and the free hydroxyl group (or its alcoxide) are needed, in the homopropar- gyl alcohol unit, to be biologically active.es
dc.description.procedenceUCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de Químicaes
dc.description.procedenceUCR::Vicerrectoría de Docencia::Salud::Facultad de Microbiologíaes
dc.identifier.citationhttps://www.scirp.org/journal/paperinformation.aspx?paperid=79145
dc.identifier.issn2161-4687
dc.identifier.urihttps://hdl.handle.net/10669/87986
dc.language.isoeng
dc.rightsacceso abierto
dc.sourceInternational Journal of Organic Chemistry, 2017, 7, 295-300.es
dc.subjectHomopropargyl Alcoholses
dc.subject1,3-Dilithiopropynees
dc.subjectAntibacterial Activityes
dc.titleSynthesis and Antibacterial Activity of Aromatic Homopropargyl Alcoholses
dc.typeartículo originales

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