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Local effects induced by coral snake venoms: Evidence of myonecrosis after experimental inoculations of venoms from five species

dc.creatorGutiérrez, José María
dc.creatorLomonte, Bruno
dc.creatorPortilla Brizuela, Elsa
dc.creatorCerdas Fallas, Luis
dc.creatorRojas Umaña, Ermila
dc.date.accessioned2017-04-19T16:38:46Z
dc.date.available2017-04-19T16:38:46Z
dc.date.issued1983
dc.description.abstractThe local effects induced by intramuscular inoculations of venons from six species of coral snakes were studied in mice. Venoms of Micrurus nlgrocinctus nigrocinctus, M. n . moquitensis, M. alleni, M. frontalis, M. aarinkauda and M. surinamensis induced prominent myonecrosis which was observed histologically. From a morphological point of view all these venons induced a similar pattern of myonecrosis, characterized by a conspicuous alteration of the intracellular structure . This myotoxic activity was corroborated by an increase in plasma creatine kinase levels 3 hr after i .m . injection of M. n. nlgrocinctus , M. n . mosquitensis, M. frontalis and M. carinicauda venoms. M. mipartitus venom did not induce myonecrosis. None of the venoms induced edema or hemorrhage at the site of injection.es_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.description.sponsorshipUniversidad de Costa Rica//UCR/Costa Ricaes_ES
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/0041010183900661
dc.identifier.doi10.1016/0041-0101(83)90066-1
dc.identifier.issn0041-0101
dc.identifier.pmid6658805
dc.identifier.urihttps://hdl.handle.net/10669/29626
dc.language.isoen_USes_ES
dc.rightsacceso embargado
dc.sourceToxicon 21(6), 777-783 (1983)es_ES
dc.subjectMicruruses_ES
dc.subjectmionecrosises_ES
dc.subjectVeneno de serpientees_ES
dc.titleLocal effects induced by coral snake venoms: Evidence of myonecrosis after experimental inoculations of venoms from five specieses_ES
dc.typeartículo original

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