Synthesis of 2-hydroxy-3-substituted naphthoquinones using the Heck reaction
Fecha
2007-06
Tipo
artículo original
Autores
Pérez Sánchez, Alice Lorena
Lamoureux Lamontagne, Guy
Zhen-Wu, Bi Yun
Título de la revista
ISSN de la revista
Título del volumen
Editor
Resumen
An efficient Heck coupling of 2-hydroxy-3-iodo-naphthoquinone with a series of electron-deficient alkenes in aqueous solution has been accomplished. The method is characterized by simple conditions and facile work-up to isolate the products in good to excellent yields. The products contain the motif present in several naphthoquinone pigments but with enhanced polarity.
Descripción
Palabras clave
Heck reaction, Hooker condensation, Naphthoquinone, 2-Hydroxy-3-iodonaphthoquinone