Listar Química por autor "Mapp, Anna K."

Mostrando ítems 1-2 de 2

    • Norstictic Acid Is a Selective Allosteric Transcriptional Regulator 

      Garlick, Julie M.; Sturlis, Steven M.; Bruno, Paul A.; Yates, Joel A.; Peiffer, Amanda L.; Liu, Yejun; Goo, Laura; Bao, LiWei; De Salle, Samantha N.; Tamayo Castillo, Giselle; Brooks, Charles L. III; Merajver, Sofia D.; Mapp, Anna K. (2021-06-17)
      Inhibitors of transcriptional protein–protein interactions (PPIs) have high value both as tools and for therapeutic applications. The PPI network mediated by the transcriptional coactivator Med25, for example, regulates ...

    • Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300 

      Majmudar, Chinmay Y.; Højfeldt, Jonas W.; Arevang, Carl J.; Pomerantz, William C.; Gagnon, Jessica K.; Schultz, Pamela J.; Cesa, Laura C.; Doss, Conor H.; Rowe, Steven P.; Vásquez Chaves, Víctor; Tamayo Castillo, Giselle; Cierpicki, Tomasz; Brooks, Charles L. III; Sherman, David H.; Mapp, Anna K. (2012-10-08)
      Although there have been recent notable successes in thediscovery of ligands that target stable, high-affinity protein-protein interactions (PPIs), the transient and moderateaffinity PPIs that underpin many fundamental ...