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Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach
(2019)
The main objective of this research is to develop an immediate release Rupatadine fumarate 10
mg tablets formulation by direct compression, through a Quality by Design approach in Costa
Rica.
Methods: According to a ...
Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
(2018)
It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ...
Furosemide Diuretic Activity Evaluation in Female Sprague-Dawley Rats
(2019)
This research article focuses on the evaluation of the diuretic activity of Furosemide administered to a group of female Sprague Dawley rats, through the use of metabolic boxes.
Methods: A hydration volume of 5 mL/100 g ...
Evaluation of the critical points in the validation of 500 mg levofloxacin tablets for dissolution profile
(2016)
The method was validated by ultraviolet spectrophotometry for the
determination of levofloxacin 500 mg tablets using dissolution profiles
to establish therapeutic equivalence. The parameters were satisfactory
according ...
Physicochemical Characterization of a Liposomal Formulation Based on Glucosamine and Vitamin D, Commercialized as a Nutritional Supplement
(2018)
In the last years, the transport and release mechanism of bioactive compounds has been studied.
The liposomes are multivesicular systems that enhance the absorption, stability, and transport of
these compounds. The ...
Quality control performed on liposomal formulations based on guarana extract, vitamins a, c, e, b1, b2, b5, b6, b12, biotin and folic acid, used as nutritional products
(2017)
The study of has increased in the last decades. One of the mechanisms that has acquired great relevance is to formulate using liposomal vesicles. Liposomes are structures that enh and transport of active compounds, which ...
Comparison of the antifungal and antibacterial effect of the essential oil and ethanolic extract of the Zingiber officinale Rhizome (Ginger) cultivated in the San Carlos zone, Costa Rica in order to standardize a hydroponic medicinal cultivation of the same
(2020)
Introduction: Ginger is a medicinal plant native to India. Its potential use in cosmetics, medicines and natural products has been reported, however depending on the conditions of cultivation the medicinal components of ...
Socioeconomic and intellectual property analysis in pharmaceutical natural products
(2018-02)
The absence of a consolidated definition of the term “natural product” is a problem to establish a relationship between this concept and intellectual property. The intellectual property includes many different categories, ...
Physicochemical characterization of therapeutic peloids from the surroundings of Costa Rica Arenal Volcano
(2015)
Costa Rica is a volcanic country, containing a variety of peloids with different physicochemical properties; also its main
source of income is the tourism. Most of their abundant natural resources have not been characterized ...
Intervenciones educativas en pacientes asmáticos no controlados en un hospital público de Costa Rica: estudio observacional, prospectivo
Educational interventions in patients with uncontrolled asthma in a public hospital in Costa Rica: observational, prospective study
(2018)
Objetivo: El presente estudio pretende evaluar una propuesta de atención farmacéutica a pacientes asmáticos para verificar su influencia sobre el control de la enfermedad.
Método: Se ejecutó un estudio cuasi experimental, ...