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Testing experience and environmental enrichment potentiated open-field habituation and grooming behaviour in rats
In laboratory rats, one of the most used paradigms to assess habituation to novelty is the open-field test. Environmental enrichment has proved to be a reliable way to enhance open-field test habituation. Experiment 1, ...
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
La administración sub-crónica de hierba de San Juan revierte las conductas de ansiedad y depresión inducidas por dos protocolos distintos de estrés crónico
Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ...
Age-dependent effects of environmental enrichment on spatial memory and neurochemistry
Although aging and environmental stimulation are well-known to affect cognitive abilities, the question of whether aging effects can be distinguished in already-mature adult rats has not been fully addressed. In the ...