Listar Medicina, ciencias biomédicas y salud pública por título
Mostrando ítems 1851-1870 de 2039
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Somatic instability of the expanded CTG triplet repeat in myotonic dystrophy type 1 is a heritable quantitative trait and modifier of disease severity
(Human Molecular Genetics, 2012 Vol. 21, No. 16. 3558–3567, 2012-05-30)Deciphering the contribution of genetic instability in somatic cells is critical to our understanding of many human disorders. Myotonic dystrophy type 1 (DM1) is one such disorder that is caused by the expansion of a CTG ... -
¿Son los nonagenarios costarricenses los seres humanos más longevos?
(2005)Con base en datos de un registro de población que se lleva en Costa Rica con propósitos electorales, este artículo reestima la mortalidad y la esperanza de vida de los nonagenarios costarricenses. El registro contiene 24.400 ... -
Soporte ventricular izquierdo de corta duración como puente a trasplante cardiaco como manejo de la falla cardiaca refractaria
(2022)La falla cardiaca refractaria es una patología cada vez más común en nuestros servicios de salud, por esta razón es necesario familiarizarnos con el manejo quirúrgico de dicha patología. El abordaje del cirujano cardiovascular ... -
Spatial access to health care in Costa Rica and its equity: a GIS-based study
(2004-04)This study assembles a geographic information system (GIS) to relate the 2000 census population (demand) with an inventory of health facilities (supply). It assesses the equity in access to health care by Costa Ricans and ... -
Spatial dimensions of family planning in Costa Rica: the value of geocoding demographic surveys
(1997)The article illustrates the value of geocoding demographic surveys and conducting spatial analyses to understand the service supply environment and contraceptive behavior. Three Costa Rican data sets are geocoded and pooled ... -
Stress-Induced Microglia Activationand Monocyte Trafficking to the BrainUnderlie the Development of Anxietyand Depression
(2016)Psychosocial stress is capable of causing immune dysregulation and increased neuroinflammatory signaling by repeated activation of the neuroendocrine and autonomic systems that may contribute to the development of anxiety ... -
Stressors Over the Life Course and Neuroendocrine System Dysregulation in Costa Rica
(Journal of Aging and Health XX(X) 1–24, 2010-05-28)Objectives: A key aspect of the increasingly popular allostatic load (AL) framework is that stressors experienced over the entire life course result in physiological dysregulation. Although core to AL theory, this idea has ... -
Studies of the Costa Rican Model I: Peace, Health and Development in Costa Rica
(1993)Costa Ricans have cultivated peace and democracy for decades. They have also achieved outstanding levels of health. Their economic well-being is not so good, however. The 1949 constitution abolished the armed forces in ... -
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
(2017-05-30)Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ... -
Subconvulsant doses of pentylenetetrazol uncover the epileptic phenotype of cultured synapsin-deficient Helix serotonergic neurons in the absence of excitatory and inhibitory inputs
(2016-09-06)Synapsins are a family of presynaptic proteins related to several processes of synaptic functioning. A variety of reports have linked mutations in synapsin genes with the development of epilepsy. Among the proposed ... -
Substance use disorder and schizophrenia: prevalence and sociodemographic characteristics in the Latin American population
(Actas Esp Psiquiatr 2011;39(2):123-30, 2011)El interés por comprender la co-morbilidad de la esquizofrenia y el trastorno en el uso de sustancias, ha aumentado debido al incremento de este diagnóstico, a los efectos negativos observados en el sujeto y a los ... -
Suero antiofidico polivalente
(2013-07-17)El suero antiofídico polivalente es eficaz en accidentes causados por todas las serpientes centroamericanas con excepción de las corales y las serpientes de mar, este suero no es eficaz contra el veneno de serpientes de ... -
Suero antiofídico anti-coral
(2013-07-17)El suero anti-coral es eficaz en los accidentes causados por las serpientes Micrurus nigrocinctus, Micrurus fulvius y Micrurus d. carinicaudus. Este suero NO ES EFICAZ para neutralizar el veneno de Micrurus ... -
Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in latinos: a family-based association study
(Bipolar Disorders 2013: 15: 206–214, 2013-02-25)Objectives: Through recent genome-wide association studies (GWASs), several groups have reported significant association between variants in the calcium channel, voltage-dependent, L-type, alpha 1C subunit (CACNA1C) and ... -
Sunitinib effectiveness and safety as first line treatment in metastatic renal cell carcinoma, in the Costa Rican population
(2016-10-21)Aim: Tyrosine kinase inhibitors are part of the armamentarium to treat metastatic renal cell carcinomas (mRCC). Costa Rica has approved sunitinib in the first line setting. The authors conducted a retrospective study to ... -
Sunscreen Use and Sweat Production in Men and Women
(2016)Context: Sunscreen lotions are important to protect the skin during outdoor exercise, but they may interfere with sweating. Objective: To measure the effect of two different water-resistant sunscreen products on local ... -
Supervivencia global en pacientes con cáncer gástrico y de la unión gastroesofágica avanzado sometidos a terapia citotóxica de segunda y tercera línea en los hospitales Dr. Max Peralta y Dr. R. A. Calderón Guardia en el período de 2012 a 2018
(2020-01-16)El cáncer gástrico es una de las neoplasias de mayor incidencia y mortalidad a nivel mundial. Ocupa el tercer lugar como causa de muerte relacionada al cáncer en el siglo XX y el cuarto lugar en incidencia a nivel mundial. ... -
Supervivencia libre de progresión y tasa de respuesta clínico-radiológica con bevacizumab adicionado a la quimioterapia en el tratamiento del cáncer colorrectal metastásico en los pacientes atendidos en hospitales de la Caja Costarricense de Seguro Social en el periodo comprendido de enero 2014 a diciembre 2018
(2020)El cáncer de colon corresponde a la tercera causa de muerte en mujeres y cuarta en hombres en Costa Rica. Sin embargo, se ha logrado mejorar la supervivencia de los pacientes con esta malignidad como consecuencia de ... -
Survival and Physical Growth in Infancy and Early Childhood Study of Birth Weight and Gestational Age in a Guatemalan Indian Village
(1975-05)Many factors contribute independently or jointly to the cause and pathogenesis of low birth weight. Attempts to identify these factors in a given population, however, are usually unsuccessful, and conclusions ...