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Liquen plano oral en paciente con psoriasis: Reporte de caso y revisión de literatura
(2020-12-23)El liquen plano oral (LPO) es un trastorno mucocutáneo inflamatorio crónico mediado por células T. Las lesiones orales suelen ser crónicas, no remisivas y pueden ser una fuente de morbilidad. El tratamiento va enfocado a ... -
Litos Retenidos Posterior a Colecistectomía Laparoscópica y sus Complicaciones
(2023)La colelitiasis es una de las patologías más frecuentes a nivel mundial y se estima que afecta aproximadamente entre un 10% a 20% de la población. En la actualidad el manejo de elección para el tratamiento de la colelitiasis ... -
Liver Metastasectomy and Systemic Therapy Improve Overall Survival Compared With Surgery Alone After Curative Liver Resection of Colorectal Metastases in a Developing Country (Costa Rica)
(2017-02)Background Resection of liver-isolated metastases of colorectal cancer (CRC) offers the greatest likelihood of cure. Nevertheless, recurrence rates after this procedure are high, and chemotherapy is a reasonable choice ... -
Líquido amniótico meconizado y su relación con la infección del sitio quirúrgico en pacientes sometidas a cesárea
(2020-01-14)En este trabajo de investigación se realizó una revisión bibliográfica acerca de la asociación entre la presencia de líquido amniótico meconizado y la infección del sitio de herida quirúrgica, con el objetivo de analizar ... -
Local and systemic pathophysiological alterations induced by a serine proteinase from the venom of the snake Bothrops jararacussu
(2007-06-01)The local and systemic pathophysiological alterations induced by BjussuSP-I, a thrombin-like serine proteinase from the venom of the snake Bothrops jararacussu, were assessed in mice. BjussuSP-I induced a mild edema but ... -
Local effects induced by coral snake venoms: Evidence of myonecrosis after experimental inoculations of venoms from five species
(1983)The local effects induced by intramuscular inoculations of venons from six species of coral snakes were studied in mice. Venoms of Micrurus nlgrocinctus nigrocinctus, M. n . moquitensis, M. alleni, M. frontalis, M. aarinkauda ... -
Local tissue damage induced by BaP1, a metalloproteinase isolated from Bothrops asper (Terciopelo) snake venom
(1995-12)The pathogenesis of hemorrhage and other local effects induced by the metalloproteinase BaP1, isolated from Bothrops asper venom, was investigated using various in vivo and in vitro models. Upon intramuscular injection in ... -
Local tissue damage induced by Bothrops snake venoms - A review
(1989-12)This review focuses on the local effects induced by Bothrops venoms. These envenomation are characterized by myonecrosis, hemorrhage and edema which develop rapidly after venom inoculation. Myonecrosis is caused (a) directly, ... -
Localization of Myotoxin I and Myotoxin II from the venom of Bothrops asper in a murine model
(2021)Phospholipases A2 (PLA2s) and PLA2-like proteins are significant components of snake venoms. Some of these proteins act as potent toxins causing muscle necrosis, which may lead to amputation in severe envenomings. Fundamental ... -
Longer leukocyte telomere length in Costa Rica's Nicoya Peninsula: A population-based study
(2013)Studies in humans suggest that leukocyte telomere length may act as a marker of biological aging. We investigated whether individuals in the Nicoya region of Costa Rica, known for exceptional longevity, had longer telomere ... -
Longitud larval de Hemilucilia segmentaria (Diptera: Calliphoridae) como indicador del intervalo post-mortem en Costa Rica
(2003-12-31)La longitud larval de Hemilucilia segmentar/a (Diptera: Calliphorldae) fue evaluada como un Indicador del intervalo post-mortem (IPM) en un modelo experimental. Se realizaron observaciones por triplicado en cadáveres de ... -
Longitudinal increases in somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 are associated with variation in age-at-onset
(2020-06-30)In myotonic dystrophy type 1 (DM1), somatic mosaicism of the (CTG)n repeat expansion is age-dependent, tissue-specific and expansion-biased. These features contribute toward variation in disease severity and confound ... -
Low endemicity and low pathogenicity of rotaviruses among rural children in Costa Rica
(1985)Rotaviruses were prospectively studied in 51 rural Costa Rican children from birth to two years. Samples of feces were collected weekly over a 33-month period. Rotavirus was detected in 45 (1.04%) of 4,317 fecal specimens; ... -
Low pH formulation of whole IgG antivenom: Impact on quality, safety, neutralizing potency and viral inactivation
(2012-03)Low pH treatment improves the tolerance to intravenous infusion, the stability, and the viral safety of various therapeutic immunoglobulins G preparations, but has never been evaluated for horse plasma-derived antivenoms. ... -
Low-cost internal controls for detection of Giardia cysts in water samples
(2019-08)Giardia cysts stained with hot carbolfuchsin were used as internal controls in a concentration method for surface water samples. The morphological integrity of stained cysts and the stain's stability and intensity were ... -
La lutte contre les maladies diarrhéiques, le cas du Costa Rica
(1985)Le taux de mortalite infantile du Costa Rica est recemment tombs a 18 p. 1000, devenant ainsi l'un des plus faible du Tiers monde. Dans cet extraordinaire progres, la reduction des maladies diarrheiques a joue un role ... -
Lys-49 phospholipases A2 as active enzymes for beta-arachidonoyl phospholipid bilayer membranes
(1997)Phospholipases A2 containing Lys-49 have been reported to be extremely weak or inactive as enzyme. We have recently shown that basic proteins I and II (BP-I and BP-II), Lys- 49-PLA2s isolated from the venom of Trimeresurus ... -
Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: a comprehensive review
(2023)Muscle necrosis is a potential clinical complication of snakebite envenomings, which in severe cases can lead to functional or physical sequelae such as disability or amputation. Snake venom proteins with the ability to ...