• Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300 

      Majmudar, Chinmay Y.; Højfeldt, Jonas W.; Arevang, Carl J.; Pomerantz, William C.; Gagnon, Jessica K.; Schultz, Pamela J.; Cesa, Laura C.; Doss, Conor H.; Rowe, Steven P.; Vásquez Chaves, Víctor; Tamayo Castillo, Giselle; Cierpicki, Tomasz; Brooks, Charles L. III; Sherman, David H.; Mapp, Anna K. (2012-10-08)
      Although there have been recent notable successes in thediscovery of ligands that target stable, high-affinity protein-protein interactions (PPIs), the transient and moderateaffinity PPIs that underpin many fundamental ...