Listar Biología por autor "143b0a51-1a3e-4cea-a0f5-7e176d48e4ac"
Mostrando ítems 1-9 de 9
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Acute stress differentially affects grooming subtypes and ultrasonic vocalisations in the open-field and home-cage test in rats
Rojas Carvajal, Mijail; Brenes Sáenz, Juan Carlos (2020-06)Grooming behaviour in rodents has been associated with emotional distress, especially in unfamiliar and aversive contexts. However, the biological function of grooming in such situations is still unclear. We hypothesised ... -
Age, experience, and neurobehavioral domain: dissociable effects of environmental enrichment and social isolation on brain and behavior in adult and aged rats
Rojas Carvajal, Mijail; Ramírez Chan, Karol Gabriela; Sequeira Cordero, Andrey; Fornaguera Trías, Jaime; Brenes Sáenz, Juan Carlos (2019)In rats, environmental enrichment (EE) is a form of physical-social stimulation used for modeling the impact of optimal developmental conditions on animal’s phenotype. When implemented during early life, EE improves animal’s ... -
Age-dependent differences on neurochemistry and behavior in rats raised with low and high levels of maternal care
Rojas Carvajal, Mijail; Brenes Sáenz, Juan Carlos; Sequeira Cordero, Andrey (2019)In laboratory rats, naturally-occurring variations in maternal care have been used to study the neurobehavioral consequences of maternal nursing and to model the early-life adversity associated with many psychiatric ... -
Behavioral changes across novelty habituation: Contextual modulation of self-grooming after a stress event
Rojas Carvajal, Mijail; Villalobos Cortés, Katherine; Fornaguera Trías, Jaime; Brenes Sáenz, Juan Carlos (2018-07)Grooming is a widespread behavior in the animal kingdom primarily geared towards the care of the body surface; nonetheless, other behavioral functions have been investigated and postulated. For example, rodents display ... -
Habituation and spatial memory in the context of emotional regulation: Behavioral and genetic mechanisms underlying context information-processing and de-arousal grooming
Rojas Carvajal, Mijail; Rodríguez Villagra, Odir Antonio; Sequeira Cordero, Andrey; Fornaguera Trías, Jaime; Brenes Sáenz, Juan Carlos (2017)Habituation is the ability to passively reduce a response after repeated or prolonged exposures to a particular stimulus. From a cognitive perspective, habituation is a basic, information-gating process that contributes ... -
Muscarinic and glutamatergic regulation of self-grooming behavior and ultrasonic vocalizations in the context of open-field habituation in rats
Brenes Sáenz, Juan Carlos; Chinchilla, Jimmy; Leandro, Rita; Fornaguera Trías, Jaime; Rojas Carvajal, Mijail (2019)We tested whether pharmacological impairment of OF-habituation after the administration (i.p.) of scopolamine (SCP; muscarinic antagonist) or MK-801 (MK; NMDA antagonist) was able to disrupt or alter grooming syntaxes. ... -
Neurobehavioral Effects of Restricted and Unpredictable Environmental Enrichment in Rats
Rojas Carvajal, Mijail; Sequeira Cordero, Andrey; Brenes Sáenz, Juan Carlos (2020-05)To study how motivational factors modulate experience-dependent neurobehavioral plasticity, we modify a protocol of environmental enrichment (EE) in rats. We assumed that the benefits derived from EE might vary according ... -
The cage test as an easy way to screen and evaluate spontaneous activity in preclinical neuroscience studies
Rojas Carvajal, Mijail; Quesada Yamasaki, Daniel; Brenes Sáenz, Juan Carlos (2021-02-17)Within behavioral neuroscience, subjects used to be randomly assigned to the experimental groups based on the premise that interindividual variability will be homogeneously distributed. However, the equivalence offered by ... -
The environmental enrichment model revisited: A translatable paradigm to study the stress of our modern lifestyle
Rojas Carvajal, Mijail; Sequeira Cordero, Andrey; Brenes Sáenz, Juan Carlos (2021-02-27)Mounting evidence shows that physical activity, social interaction and sensorimotor stimulation provided by environmental enrichment (EE) exert several neurobehavioural effects traditionally interpreted as enhancements ...