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Importance of mevalonate pathway lipids on the growth and survival of primary and metastatic gastric carcinoma cells
(2021)
Purpose: This preclinical study aims to determine the effect of drugs that alter isoprenoids and cholesterol metabolism in the homeostasis of gastric carcinoma cell lines in the search for new therapeutic targets for stomach ...
Molecular Recognition of Surface Trans-Sialidases in Extracellular Vesicles of the Parasite Trypanosoma cruzi Using Atomic Force Microscopy (AFM)
(2022-06-28)
Trans-sialidases (TS) are important constitutive macromolecules of the secretome present on the surface of Trypanosoma cruzi (T. cruzi) that play a central role as a virulence factor in Chagas disease. These enzymes have ...
High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays
(2016-11-08)
Snakebite envenoming is a serious condition requiring medical attention and administration of
antivenom. Current antivenoms are antibody preparations obtained from the plasma of animals
immunised with whole venom(s) and ...