Browsing Microbiología by Author "9f454115-d2fa-468b-9de1-765387c25c1f"

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    • Brucella canis Is an Intracellular Pathogen That Induces a Lower Proinflammatory Response than Smooth Zoonotic Counterparts 

      Chacón Díaz, Carlos; Altamirano Silva, Pamela; González Espinoza, Gabriela; Medina, María Concepción; Alfaro Alarcón, Alejandro; Bouza Mora, Laura; Jiménez Rojas, César; Wong Araya, Melissa; Barquero Calvo, Elías; Rojas Campos, Norman; Guzmán Verri, Caterina; Moreno Robles, Edgardo; Chaves Olarte, Esteban (2015-11-10)
      Canine brucellosis caused by Brucella canis is a disease of dogs and a zoonotic risk. B. canis harbors most of the virulence determinants defined for the genus, but its pathogenic strategy remains unclear since it has not ...

    • Intracellular passage triggers a molecular response in that increases its infectiousness 

      Altamirano Silva, Pamela; Cordero Serrano, Marlen; Méndez Montoya, Joselyn; Chacón Díaz, Carlos; Guzmán Verri, Caterina; Moreno Robles, Edgardo; Chaves Olarte, Esteban (2021)
      Brucella abortus is a facultative extracellular-intracellular pathogen that encounters a diversity of environments within the host cell. We report that bacteria extracted from infected cells at late stages (48 h post-infection) ...

    • Neutrophils as Trojan Horse Vehicles for Brucella abortus Macrophage Infection 

      Gutiérrez Jiménez, Cristina; Mora Cartín, Ricardo; Altamirano Silva, Pamela; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Moreno Robles, Edgardo; Barquero Calvo, Elías (2019-05-07)
      Brucella abortus is a stealthy intracellular bacterial pathogen of animals and humans. This bacterium promotes the premature cell death of neutrophils (PMN) and resists the killing action of these leukocytes. B. abortus-infected ...

    • Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation 

      Altamirano Silva, Pamela; Meza Torres, Jazmín Andrea; Zúñiga Pereira, Ana Mariel; Zamora Jaen, Sigrid; Pietrosemoli, Natalia; Cantos González, Gabriela; Peltier, Johann; Pizarro Cerdá, Javier; Moreno Robles, Edgardo; Chacón Díaz, Carlos; Guzmán Verri, Caterina; Chaves Olarte, Esteban (2023-04)
      Brucella abortus is a zoonotic pathogen whose virulence depends on its ability to survive intracellularly at the endoplasmic reticulum derived compartment. The two-component system BvrR/BvrS (BvrRS) is essential for ...

    • Senses the Intracellular Environment through the BvrR/BvrS Two-Component System, Which Allows To Adapt to Its Replicative Niche 

      Altamirano Silva, Pamela; Meza Torres, Jazmín Andrea; Castillo Zeledón, Amanda; Ruiz Villalobos, Nazareth; Zúñiga Pereira, Ana Mariel; Chacón Díaz, Carlos; Moreno Robles, Edgardo; Guzmán Verri, Caterina; Chaves Olarte, Esteban (2018-03-22)
      Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...