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Transient exposure to coffee as a trigger of a first nonfatal myocardial infarction
dc.creator | Baylin, Ana | |
dc.creator | Hernández Díaz, Sonia | |
dc.creator | Kabagambe, Edmond K. | |
dc.creator | Siles Díaz, Xinia | |
dc.creator | Campos Núñez, Hannia | |
dc.date.accessioned | 2020-05-22T16:27:04Z | |
dc.date.available | 2020-05-22T16:27:04Z | |
dc.date.issued | 2006 | |
dc.identifier.citation | https://journals.lww.com/epidem/Fulltext/2006/09000/Transient_Exposure_to_Coffee_as_a_Trigger_of_a.7.aspx | |
dc.identifier.issn | 1044-3983 | |
dc.identifier.issn | 1705-0506 | |
dc.identifier.uri | https://hdl.handle.net/10669/81087 | |
dc.description.abstract | Background: The effects of coffee on myocardial infarction are uncertain. We hypothesize that coffee in the presence of predisposing factors can induce a cascade of events that, through sympathetic nervous activation, can induce the onset of myocardial infarction. Methods: We recruited 503 incident cases of nonfatal myocardial infarction between 1994 and 1998 in Costa Rica. We used a case-crossover design to calculate relative risks (RRs) and 95% confidence intervals (95% CIs). Results: The RR of myocardial infarction in the hour after coffee intake was 1.49 (95% CI = 1.17–1.89). Occasional coffee drinkers (≤1 cup/day, n = 103) had a RR of myocardial infarction of 4.14 (2.03–8.42), moderate coffee drinkers (2–3 cups/day, n = 280) had a RR of 1.60 (1.16–2.21), and heavy coffee drinkers (≥4 cups/d, n = 120) had a RR of 1.06 (0.69–1.63; P = 0.006, test of homogeneity). Patients with 3 or more risk factors (n = 101) had a RR of myocardial infarction of 2.10 (1.30–3.39), whereas patients with fewer than 3 risk factors (n = 396) had a RR of 1.39 (1.04–1.82; P = 0.15, test of homogeneity); and RR was 1.72 (1.30–2.30) among sedentary patients compared with 1.07 (0.66–1.72) among nonsedentary (P = 0.10, test of homogeneity). Conclusions: The findings indicate that coffee intake may trigger myocardial infarction. The association is particularly strong among people with light/occasional intake of coffee (≤1 cup/day), with sedentary lifestyle, or with 3 or more risk factors for coronary heart disease. | es_ES |
dc.language.iso | en_US | es_ES |
dc.source | Epidemiology, vol.17(5), pp.506-511 | es_ES |
dc.subject | Myocardial Infarction | es_ES |
dc.subject | Coffee | es_ES |
dc.title | Transient exposure to coffee as a trigger of a first nonfatal myocardial infarction | es_ES |
dc.type | artículo original | |
dc.identifier.doi | 10.1097/01.ede.0000229444.55718.96 | |
dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Centro Centroamericano de Población (CCP) | es_ES |
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