Listar Microbiología por autor "Quadros, Luiz H. B."
Mostrando ítems 1-2 de 2
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In vivo treatment with varespladib, a phospholipase A2 inhibitor, prevents the peripheral neurotoxicity and systemic disorders induced by Micrurus corallinus (coralsnake) venom in rats
Silva Carvalho, Rosimeire; Gaspar, Matheus Z.; Quadros, Luiz H. B.; Lobo, Luís G. G.; Rogério, Letícia M.; Santos, Najla T. S.; Zerbinatti, Maria C.; Santarém, Cecília L.; Silva, Elisangela O.; Gerez, Juliana Rubira; Da Silva Junior, Nelson Jorge; Lomonte, Bruno; Rowan, Edward Gerard; Floriano, Rafael Stuani (2022-03)In this study, we investigated the action of varespladib (VPL) alone or in combination with a coral snake antivenom (CAV) on the local and systemic effects induced by Micrurus corallinus venom in rats. Adult male Wistar ... -
Partial efficacy of a Brazilian coralsnake antivenom and Varespladib to neutralize distinct toxic effects induced by a sublethal Micrurus dumerilii carinicauda envenoming in rats
Silva Carvalho, Rosimeire; Gaspar, Matheus Z.; Quadros, Luiz H. B.; Lobo, Luís G. G.; Giuffrida, Rogério; Santarém, Cecília L.; Silva, Elisangela O.; Gerez, Juliana Rubira; Silva, Nelson J.; Hyslop, Stephen; Lomonte, Bruno; Floriano, Rafael Stuani (2022)In this work, we reported the efficacy of a combination of Brazilian therapeutic coralsnake antivenom (CAV) and varespladib (phospholipase A2 inhibitor – VPL) in partially neutralizing selected toxic effects of Micrurus ...