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Physiological wear-and-tear and later subjective health in mid-life: Findings from the 1958 British birth cohort
(2016)
Our body adapts continuously to environmental challenges and stressful conditions. Allostatic load (AL) is a concept that aims to capture the overall physiological wear-and-tear of the body triggered by the repeated ...
Patient Organizations’ Barriers in Pharmacovigilance and Strategies to Stimulate Their Participation
(2020)
European drug regulations aim for a patient-centered approach, including involving patients in the pharmacovigilance (PV) systems. However many patient organizations have little experience on how they can participate in ...
High 18:2 trans fatty acids are associated with increased risk of nonfatal acute myocardial infarction in Costa Rican adults
(2003)
Trans-fatty acid intake is associated with coronary heart disease (CHD), but the atherogenic potential of individual trans-fatty acids (FA) from partially hydrogenated oils (18:1 and 18:2) or meat and dairy products (16:1 ...
Venom diversity in the neotropical genus Tityus: implications for antivenom design emerging from molecular and immunochemical analyses across endemic areas of scorpionism
(2020)
Scorpions of the Neotropical genus Tityus are responsible for most severe envenomations in the Caribbean, South America, and Lower Central America (LCA). Although Tityus is taxonomically complex, contains high toxin ...
The Type of Oil Used for Cooking Is Associated with the Risk of Nonfatal Acute Myocardial Infarction in Costa Rica
(2005)
Palm oil and soybean oil are the 2 most widely used cooking oils in the world. Palm oil is consumed mainly in developing countries, where morbidity and mortality due to cardiovascular disease (CVD) are on the rise. Although ...
Vector-borne pathogens in dogs from Costa Rica: First molecular description of Babesia vogeli and Hepatozoon canis infections with a high prevalence of monocytic ehrlichiosis and the manifestations of co-infection
(2014)
Infection with canine vector-borne pathogens was evaluated in dogs from four different
regions of Costa Rica by PCR. Demographic data, clinical signs, packed cell volume values,
and the presence of tick infestation were ...
Detection of Dirofilaria immitis and other arthropod-borne filarioids by an HRM real-time qPCR, blood-concentrating techniques and a serological assay in dogs from Costa Rica
(2015)
Background: Canine filarioids are important nematodes transmitted to dogs by arthropods. Diagnosis of canine
filariosis is accomplished by the microscopic identification of microfilariae, serology or PCR for filarial-DNA. ...
The vanishing advantage of longevity in Nicoya, Costa Rica: A cohort shif
(2023)
BACKGROUND
The Nicoya region in Costa Rica has been identified as one of a handful of hotspots of
extreme longevity. The evidence supporting this status comes mostly from observing the
1990 and 2000 decades and cohorts ...
Nutritional lifestyle patterns and cancer: confounding effect of social determinants across the life course in women from the 1958 British birth cohort study
(2020)
Objective: To examine the confounding role of social determinants across the life course in the relationship of nutritional lifestyle patterns with cancer in women.
Methods: In the National Child Development Study, 37 ...