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Enfermedad de Chagas en Costa Rica: Estudio comparativo en dos épocas diferentes
Chagas disease in Costa Rica: comparative studyin two different stages
(2006)
Para actualizar la situación de la Enfermedad de Chagas en Costa Rica se realizó un estudio serológico y epidemiológico parcial en 4 zonas de riesgo en el país. Un total de 1.561 estudiantes de 6 a 12 años fueron estudiados ...
Association of interleukin-1B and interleukin-1RN polymorphisms with gastric cancer in a high-risk population of Costa Rica
(Clinical and Experimental Medicine 5 p.169-176, 2005-09-13)
Several risk factors have been associated with gastric cancer, among them Helicobacter pylori infection. This bacterium yields inflammation, the degree of which depends on the bacterial strain and the severity of the host ...
Two phospholipase A2 inhibitors from the plasma of Cerrophidion (Bothrops) godmani which selectively inhibit two different group-II phospholipase A2 myotoxins from its own venom: isolation, molecular cloning and biological properties
(2000-03-15)
Myotoxic phospholipases A2 (PLA2s; group II) account for most of the muscle-tissue damage that results from envenomation by viperid snakes. In the venom of the Godman's viper (Cerrophidion godmani, formerly Bothrops godmani), ...
Genética de la esquizofrenia: avances en el estudio de genes candidatos
(Rev. biol. trop v.52 n.3, p. 467-473 sep. 2004, 2004)
Genetics of Schizophrenia: advances in the study of candidate genes. Schizophrenia is one of the
most severe mental disorders that affect 1% of the population worldwide. It is clear that both genetic and
environmental ...
Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum
(2008)
Dawley rats were reared from weaning in either social isolation, standard laboratory conditions, or environmental enrichment. Open-field activity
was assessed at postnatal days 37, 65, 93 and 107 and 1 h before the last ...
Snake venom components enhance pain upon subcutaneous injection: an initial examination of spinal cord mediators
(2004-09)
Snakebites are a relevant public health problem in Central and South America. Snake bite envenomations cause intense pain, not relieved by anti-venom. The fangs of many species are short, causing subcutaneous injection. ...
Microsomal epoxide hydrolase genotype and risk of myocardial infarction
(2007)
DNA damage caused by mutagens found in tobacco smoke may contribute to the development of coronary heart disease (CHD). Microsomal epoxide hydrolase (EPHX1) is involved in the metabolism of tobacco smoke mutagens and an ...
Structure of myotoxin-II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom
(2006)
Lys49 snake-venom phospholipase A2 (PLA2) homologues are highly myotoxic
proteins which, although lacking catalytic activity, possess the ability to disrupt
biological membranes, inducing significant muscle-tissue loss ...
Paracoccidiodomicosis (Reporte de siete casos)
Paracoccidiodomycosis (Report of seven cases)
(Revista Médica de Costa Rica y Centroamérica, tomo 65, número 582, p.41-47, 2008)
Paracoccidiomycosis is an illness produced by dimorphic fungi (Paracoccidiodes Brasiliensis) that can affect various organs, among them skin and mucous membranes, lymph nodes, lungs, bones, adrenal glands, the vascular and ...
Impacto de la revolución genómica en la salud de los países latinoamericanos
(Revista Costarricense de Ciencias Médicas 26 (3-4) p. 53-54, 2005-07)
El objetivo de este trabajo es analizar un tema de actualidad y'de interés para los profesionales de la salud, relacionados con la "nueva genética". Se tocan aspectos coma el proyecto del genoma humano, el nacimiento de ...