Listar por autor "b78e1970-41f4-4602-9893-11629325034e"
Mostrando ítems 1-20 de 24
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Acanthamoeba genotype T4 keratitis in a patient with Thygeson’s superficial punctate keratitis
Rodríguez Mena, Diego; Retana Moreira, Lissette; Abrahams Sandí, Elizabeth (2017-01)A case of amoebic keratitis due to Acanthamoeba genotype T4 is reported. The patient is a 74-year old woman with Thygeson’s superficial punctate keratitis. Corneal scrapings were employed for the diagnosis, which included ... -
Amebas de vida libre como agentes de encefalitis en el ser humano
Abrahams Sandí, Elizabeth; Retana Moreira, Lissette (2014-07)Este artículo de revisión se enfoca en las amebas de vida libre, un tipo de protozoarios que habitan diferentes tipos de suelo y fuentes de agua. Estos organismos tienen dos estadios evolutivos: trofozoíto y quiste, siendo ... -
Aplicación de la topología molecular en la predicción de la actividad antiprotozoaria de derivados del benzimidazol
Debenedetti López, Ángela; Iglesias Gómez, Irene; Retana Moreira, Lissette; Gálvez Álvarez, Jorge; García Domenech, Ramón (2013-03)Se ha aplicado la topología molecular a la búsqueda de nuevos derivados del benzimidazol con actividad antiprotozoaria frente a Trichomonas vaginalis y Giardia intestinalis. A partir de los resultados del análisis lineal ... -
Biophysical and Biochemical Comparison of Extracellular Vesicles Produced by Infective and Non-Infective Stages of Trypanosoma cruzi
Retana Moreira, Lissette; Prescilla Ledezma, Alexa; Cornet Gómez, Alberto; Linares Ordoñez, Fátima; Jódar Reyes, Ana Belén; Fernández Sánchez, Jorge; Ibarrola Vanucci, Ana Karina; De Pablos Torró, Luis Miguel; Osuna Carrillo de Albornoz, Antonio (2021-05-13)Extracellular vesicles (EVs) are small lipid vesicles released by either any prokaryotic or eukaryotic cell, or both, with a biological role in cell-to-cell communication. In this work, we characterize the proteomes and ... -
Caso clínico: Rinoescleroma
Segura Vílchez, John; González Rojas, Paulina; Retana Moreira, Lissette (2013-01)The case of a 19–year–old male patient from a rural area is presented. He had a 3-year history of nasal obstruction, episodes of facial inflammation, epistaxis, fetid rhinorrhea, hearing loss in the right ear, bilateral ... -
Characterization and functional analysis of the proteins Prohibitin 1 and 2 in Trypanosoma cruzi
Ibarrola Vanucci, Ana Karina; De Pablos Torró, Luis Miguel; Retana Moreira, Lissette; Cornet Gómez, Alberto; Cruz Bustos, Teresa; Schijman, Alejandro G.; Ramírez, José L.; Vílchez, Susana; Osuna Carrillo de Albornoz, Antonio (2020-04-08)Background: Chagas disease is the third most important neglected tropical disease. There is no vaccine available, and only two drugs are generally prescribed for the treatment, both of which with a wide range of side ... -
Characterization of Extracellular Vesicles Secreted by a Clinical Isolate of Naegleria fowleri and Identification of Immunogenic Components within Their Protein Cargo
Retana Moreira, Lissette; Steller Espinoza, María Fernanda; Chacón Camacho, Natalia; Cornet Gómez, Alberto; Sáenz Arce, Giovanni; Osuna Carrillo de Albornoz, Antonio; Lomonte, Bruno; Abrahams Sandí, Elizabeth (2022-06)Abstract: Extracellular vesicles (EVs) are small lipid vesicles released by both prokaryotic and eu-karyotic cells, involved in intercellular communication, immunomodulation and pathogenesis. In this study, we performed a ... -
Desarrollo y evaluación de un método de obtención de larvas estériles de Lucilia eximia para su uso en terapia larval
Retana Moreira, Lissette; Belfort Arguedas, Kattia; Calderón Arguedas, Ólger; Troyo Rodríguez, Adriana; Gamboa Coronado, María del Mar (2014-06-01)Objetivo: desarrollar un método de tratamiento de huevos de Lucilia eximia para la obtención de larvas estériles y evaluar la capacidad de supervivencia de dichas larvas en condiciones de refrigeración a 4°C. Métodos: se ... -
Diagnóstico de laboratorio de coccidios intestinales
Retana Moreira, Lissette (2013-01)Los coccidios intestinales son un grupo de parásitos unicelulares que infectan el tracto gastrointestinal de diferentes especies animales, incluyendo el ser humano. Los coccidios se transmiten por la ingestión de quistes ... -
Extracellular vesicles in chagas disease: a new passenger for an old disease
De Pablos Torró, Luis Miguel ; Retana Moreira, Lissette; Osuna Carrillo de Albornoz, Antonio (2018-06-01)Extracellular vesicles (EVs) are small lipid vesicles released by prokaryotic and eukaryotic cells containing nucleic acids, proteins, and small metabolites essential for cellular communication. Depending on the targeted ... -
Extracellular vesicles of Trypanosoma cruzi and immune complexes they form with sialylated and non-sialylated IgGs increase small peritoneal macrophage subpopulation and elicit different cytokines profiles
Cornet Gomez, Alberto; Retana Moreira, Lissette; Gómez Samblás, Mercedes; Osuna Carrillo de Albornoz, Antonio (2023)American trypanosomiasis, or Chagas disease, is caused by the protozoan parasite Trypanosoma cruzi and is characterized by the presence of cardiac or gastrointestinal symptoms in a large number of patients during the chronic ... -
Extracellular vesicles of Trypanosoma cruzi tissue-culture cell-derived trypomastigotes: Induction of physiological changes in non-parasitized culture cells
Retana Moreira, Lissette; Rodríguez Serrano, Fernando; Osuna Carrillo de Albornoz, Antonio (2019-02-21)Background: Trypanosoma cruzi is the obligate intracellular parasite that causes Chagas disease. The pathogenesis of this disease is a multifactorial complex process that involves a large number of molecules and particles, ... -
Extracellular vesicles of trypomastigotes of Trypanosoma cruzi induce changes in ubiquitin-related processes, cell-signaling pathways and apoptosis
Cornet Gomez, Alberto; Retana Moreira, Lissette; Kronenberger, Thales; Osuna Carrillo de Albornoz, Antonio (2023)Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. The disease has an acute and a chronic phase in which approximately 30% of the chronic patients suffer from heart disease and/or gastrointestinal symptoms. ... -
Fatal meningoencephalitis in child and isolation of Naegleria fowleri from hot springs in Costa Rica
Abrahams Sandí, Elizabeth; Retana Moreira, Lissette; Castro Castillo, Alfredo; Reyes Batlle, María; Lorenzo Morales, Jacob (2015-02)In summary, this investigation identified an N. fowleri ameba in water sources at a resort in Costa Rica that had been visited by a child from the United States who died of PAM as a results of N. fowleri infection. These ... -
In vitro effects of environmental isolates of Acanthamoeba T4 and T5 over human erythrocytes and platelets
Alvarado Ocampo, Johan; Retana Moreira, Lissette; Abrahams Sandí, Elizabeth (2020-01-21)Free-living amoebae of the genus Acanthamoeba have been associated with keratitis and encephalitis. Some factors related to their pathogenic potential have been described, including the release of hydrolytic enzymes, and ... -
Isolation and molecular characterization of Acanthamoeba and Balamuthia mandrillaris from combination shower units in Costa Rica
Retana Moreira, Lissette; Abrahams Sandí, Elizabeth; Cabello Vílchez, Alfonso Martín; Reyes Batlle, María; Valladares Hernández, Basilio; Martínez Carretero, Enrique; Piñero Barroso, José Enrique; Lorenzo Morales, Jacob (2014-08-19)Free living amoebae (FLA) are ubiquitous protozoa, which may behave as parasites under certain conditions. Four genera are recognized as causal agents of infections in humans and animals: Naegleria, Sappinia, Acanthamoeba ... -
Isolation and Molecular Characterization of Acanthamoeba Strains from Dental Units in Costa Rica
Retana Moreira, Lissette; Abrahams Sandí, Elizabeth; Castro Artavia, Esteban; Fernández Sánchez, Ana; Castro Castillo, Alfredo; Reyes Batlle, María; Lorenzo Morales, Jacob (2015-03)Free-living amoebae are protozoa widely distributed in nature, which can be found in a variety of environments. Four genera are recognized as causal agents of infections in humans and animals: Acanthamoeba, Naegleria, Balam ... -
Isolation of Acanthamoeba T5 from Water: Characterization of Its Pathogenic Potential, Including the Production of Extracellular Vesicles
Retana Moreira, Lissette; Vargas Ramírez, Daniel; Linares Ordoñez, Fátima; Prescilla Ledezma, Alexa; Vaglio Garro, Annette; Osuna Carrillo de Albornoz, Antonio; Lorenzo Morales, Jacob; Abrahams Sandí, Elizabeth (2020-01-23)Acanthamoeba is a genus of free-living amoebae widely distributed in nature, associated with the development of encephalitis and keratitis. Despite the fact that it is common to find genotype T5 in environmental samples, ... -
Molecular Recognition of Surface Trans-Sialidases in Extracellular Vesicles of the Parasite Trypanosoma cruzi Using Atomic Force Microscopy (AFM)
Prescilla Ledezma, Alexa; Linares Ordoñez, Fátima; Ortega Muñoz, Mariano; Retana Moreira, Lissette; Jódar Reyes, Ana Belén; Hernández Mateo, Fernando; Santoyo González, Francisco; Osuna Carrillo de Albornoz, Antonio (2022-06-28)Trans-sialidases (TS) are important constitutive macromolecules of the secretome present on the surface of Trypanosoma cruzi (T. cruzi) that play a central role as a virulence factor in Chagas disease. These enzymes have ... -
Potentially pathogenic Acanthamoeba genotype T4 isolated from dental units and emergency combination showers
Castro Artavia, Esteban; Retana Moreira, Lissette; Lorenzo Morales, Jacob; Abrahams Sandí, Elizabeth (2017-12)Background: Acanthamoeba is the genus of free-living amoebae that is most frequently isolated in nature. To date, 20 Acanthamoeba genotypes have been described. Genotype T4 is responsible for approximately 90% of encephalitis ...