A new method for the preparation of 1,3-dilithiopropyne: an efficient synthesis of homopropargyl alcohols
artículo científico
Fecha
2001Autor
Cabezas Pizarro, Jorge A.
Pereira, Albán R.
Amey, Adam R.
Metadatos
Mostrar el registro completo del ítemResumen
Controlled dilithiation of propargyl bromide with two equivalents of n-butyllithium, in the presence of TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts efficiently with aldehydes and ketones to produce homopropargyl alcohols in a single step route and in high yields.
Controlled dilithiation of propargyl bromide with n-BuLi, in the presence of TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts efficiently with aldehydes and ketones to produce homopropargyl alcohols in a single step route in high yields.
External link to the item
10.1016/S0040-4039(01)01429-0Colecciones
- Química [322]