(1S,3R)-N-{(3S,10S,12S,13R,17R)-12-Hydroxy-17- [(R)-5-hydroxypentan-2-yl]-10,13-dimethylhexa- decahydro-1H-cyclopenta[a]phenanthren-3-yl}- adamantane-1-carboxamide 0.25-hydrate
artículo original
Fecha
2022-10-12Autor
Campos Fernández, Cristian Saúl
Procúpez Schtirbu, Rolando
Soto Tellini, Victor Hugo
Salazar Camacho, Juan Carlos
Jancik, Vojtech
Metadatos
Mostrar el registro completo del ítemResumen
The title compound, C 35H 57 NO 3 0.25H 2O, was synthesized from deoxycholic
acid followed by a protection, a Mitsonobu substitution, a Staudinger reduction,
formation of an amide and final reduction in the lateral chain. The compound
crystallizes in the P1 space group with four steroid molecules and one water
molecule in the triclinic cell unit. The crystal structure features O—H O
hydrogen bonding. The crystal studied was refined as a non-merohedral twin
External link to the item
doi.org/10.1107/cm_01Colecciones
- Química [360]