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dc.creatorMadrigal Redondo, German
dc.creatorVargas Zúñiga, Rolando
dc.creatorCarazo Berrocal, Gustavo
dc.creatorRamírez Arguedas, Nils Antonio
dc.date.accessioned2022-02-28T21:12:33Z
dc.date.available2022-02-28T21:12:33Z
dc.date.issued2017
dc.identifier.citationhttp://saspublisher.com/sajp-62/es_ES
dc.identifier.issn2320-4206
dc.identifier.urihttps://hdl.handle.net/10669/85905
dc.description.abstractThe determination of the spatial configuration of the compounds structures used in the production of drugs is of utmost importance due to the different physical characteristics that each have in their solid state and therefore the different qualities of each one for its use as pharmaceutical raw material. This study aimed to identify the polymorphic crystalline form of Etoricoxib raw material, a non-steroidal anti-inflammatory drug (NSAIDs) selective inhibitor of cyclooxygenase 2 (COX2) enzyme widely used in the present, which was done through four different instrumental analytical techniques: X-ray diffractometry, differential scanning calorimetry, thermogravimetry and infrared spectroscopy, comparing and studying the results obtained from the analysis with those found in the literature. Using the data obtained with these four techniques it was demonstrated that the study sample exists predominantly in the 1 anhydrous Etoricoxib form.es_ES
dc.language.isoenges_ES
dc.sourceScholars Academic Journal of Pharmacy (SAJP), vol.6(2), pp.53-61es_ES
dc.subjectDifferential scanning calorimetryes_ES
dc.subjectEtoricoxibes_ES
dc.subjectX-ray scattering patternes_ES
dc.subjectInfrared spectroscopyes_ES
dc.subjectPharmaceutical polymorphismes_ES
dc.subjectThermogravimetryes_ES
dc.titleIdentification of etoricoxib polymorphic crystalline form in pharmaceutical raw materialses_ES
dc.typeartículo científicoes_ES
dc.identifier.doi10.21276/sajp.2017.6.2.3
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones Farmacéuticas (INIFAR)es_ES
dc.description.procedenceUCR::Vicerrectoría de Docencia::Salud::Facultad de Farmaciaes_ES


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