Evaluation of mucilages isolated from seeds of Hyptis suaveolens, Salvia hispanica and Linum usitatissimum as pharmaceutical excipients in solid dose and liquid formulations

Abstract

In this work, the performance of mucilages obtained from the seeds of Hyptis suaveolens, Linum usitatissimum and salvia hispanica were evaluated for their potential use as stabilizers in liquid formulations and as binders and disintegrants in solid pharmaceutical forms. The behavior of both liquid and solid formulations prepared with the extracted mucilages was examined and compared with reference excipients showing, in most cases, very similar performance. In addition, parallel investigation of these mucilages in both liquid and solid pharmaceutical forms showed some relationships between their physico-chemical properties and the performance of the final formulation.