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dc.creatorMoncada Jiménez, José
dc.creatorPlaisance, Eric Paul
dc.creatorAraya Ramírez, Felipe
dc.creatorTaylor, James K.
dc.creatorRatcliff, Lance
dc.creatorMestek, Michael L.
dc.creatorGrandjean, Peter Walter
dc.creatorAragón Vargas, Luis Fernando
dc.description.abstractThe purpose of the study was to compare the acute hepatic response to diet modification and exercise-induced endotoxemia, and to determine if associations exist between liver damage markers, body core temperature, and IL-6 responses to a laboratory-based duathlon. Eleven moderately-trained healthy males followed a low-carbohydrate (CHO) and a high CHO diet to change their glycogen stores two-days before completing a duathlon. Blood samples were obtained at rest, immediately after and 1- and 2-h following the duathlon for determination of endotoxin-lipopolysaccharide binding protein (LPS-LBP) complex, IL-6, and liver integrity markers AST, ALT, and AST/ALT ratio. Hydration status and body core temperature were assessed at rest, during, and after the duathlon. Athletes were more dehydrated and had higher AST/ALT ratios in the lowcompared to the high-CHO diet trial regardless of the measurement time (p<0.05). IL-6 increased from resting to immediately after, 1- and 2-h following duathlon regardless of the diet (p<0.05). A higher LPS-LBP complex concentration was observed from rest to immediately after the duathlon. No significant correlations were found between LPS-LBP complex levels and body core temperature. In conclusion, athletes on a low-CHO diet showed higher hepatic structural damage and finished more dehydrated compared to athletes on a high-CHO diet. Body core temperature and LPS-LBP complex levels were unrelated beyond the increase in body core temperature explained by exercise. No significant associations were found between body core temperature, IL-6 and LPS-LBP complex concentrations.es_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.sourceBiology of Sport, Vol 27(2), pp. 111-118es_ES
dc.subject796.607 8 Ciclismo y actividades relacionadases_ES
dc.titleAcute Hepatic Response to Diet Modification and Exercise-induced Endotoxemia during a Laboratory-based Duathlones_ES
dc.typeartículo científico
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Centro de Investigación en Ciencias del Movimiento Humano (CIMOHU)es_ES

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional