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dc.creatorMoncada Jiménez, José
dc.creatorPlaisance, Eric Paul
dc.creatorMestek, Michael L.
dc.creatorAraya Ramírez, Felipe
dc.creatorRatcliff, Lance
dc.creatorTaylor, James K.
dc.creatorGrandjean, Peter Walter
dc.creatorAragón Vargas, Luis Fernando
dc.description.abstractThe aim of the study was to investigate the association between the initial metabolic state and exercise-induced endotoxaemia on the appearance of gastrointestinal symptoms (GIS) during exer-cise. Eleven males (36.6 ± 4.9 yrs, 1.7 ± 0.1 m, 74.5 ± 7.7 kg, DEXA body fat % 17.2 ± 6.6, VO2max 57.4 ± 7.4 ml·kg-1·min-1) underwent two isoenergetic diets designed to change their initial metabolic status by either depleting or maintaining their hepatic and muscular glycogen content. These diets and accompanying exercise sessions were performed by each participant in the days before completing a laboratory-based duathlon (5-km run, 30-km cycling, 10-km run).Blood samples were obtained before, immediately and 1- and 2-h following the duathlon for determi-nation of insulin (IN), glucagon (GL), endotoxin, aspartic ami-notransferase (AST), and alanine aminotransferase (ALT) mark-ers. GIS were assessed by survey before and after exercise. Diet content produced a different energy status as determined by macronutrient content and the IN/GL ratio (p < 0.05), and mild exercise-induced endotoxaemia was observed in both experi-mental duathlons. Regardless of the diet, the AST/ALT ratio following exercise and in the recovery phase indicated hepato-cyte and liver parenchyma structural damage. In spite of GIS, no significant correlations between endotoxin levels and GIS were found. In conclusion, increased markers of endotoxaemia ob-served with the high-intensity exercise were unrelated to hepatic function and/or GIS before and after exercise.es_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.sourceJournal of Sports Science and Medicine, Vol 8, pp 252-258es_ES
dc.subjectliver structurees_ES
dc.subjectestructura hepáticaes_ES
dc.subject616.330 76 Enfermedades del estómagoes_ES
dc.titleInitial metabolic state and exercise-induced endotoxaemia are unrelated to gastrointestinal symptoms during exercisees_ES
dc.typeartículo científico
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Centro de Investigación en Ciencias del Movimiento Humano (CIMOHU)es_ES

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional