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dc.creatorKrasner, Stuart W.
dc.creatorFen Lee, Tiffany Chih
dc.creatorWesterhoff, Paul
dc.creatorFischer, Natalia
dc.creatorHanigan, David
dc.creatorKaranfil, Tanju
dc.creatorBeita Sandí, Wilson
dc.creatorTaylor Edmonds, Liz
dc.creatorAndrews, Robert C.
dc.date.accessioned2018-04-03T21:15:52Z
dc.date.available2018-04-03T21:15:52Z
dc.date.issued2016-07-28
dc.identifier.citationhttps://pubs.acs.org/doi/10.1021/acs.est.6b02508
dc.identifier.issn1520-5851
dc.identifier.issn0013-936X
dc.identifier.urihttps://hdl.handle.net/10669/74410
dc.description.abstractCertain unregulated disinfection byproducts (DBPs) are more of a health concern than regulated DBPs. Brominated species are typically more cytotoxic and genotoxic than their chlorinated analogs. The impact of granular activated carbon (GAC) on controlling the formation of regulated and selected unregulated DBPs following chlorine disinfection was evaluated. The predicted cyto- and genotoxicity of DBPs was calculated using published potencies based on the comet assay for Chinese hamster ovary cells (assesses the level of DNA strand breaks). Additionally, genotoxicity was measured using the SOS-Chromotest (detects DNA-damaging agents). The class sum concentrations of trihalomethanes, haloacetic acids, and unregulated DBPs, and the SOS genotoxicity followed the breakthrough of dissolved organic carbon (DOC), however the formation of brominated species did not. The bromide/DOC ratio was higher than the influent through much of the breakthrough curve (GAC does not remove bromide), which resulted in elevated brominated DBP concentrations in the effluent. Based on the potency of the haloacetonitriles and halonitromethanes, these nitrogen-containing DBPs were the driving agents of the predicted genotoxicity. GAC treatment of drinking or reclaimed waters with appreciable levels of bromide and dissolved organic nitrogen may not control the formation of unregulated DBPs with higher genotoxicity potencies.es_ES
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior, Ministério da Educação//CAPES/Brasiles_ES
dc.description.sponsorshipUniversidad de Costa Rica//UCR/Costa Ricaes_ES
dc.description.sponsorshipUniversity of Toronto//UofT/Canadáes_ES
dc.language.isoen_USes_ES
dc.sourceEnvironmental Science & Technology, Vol. 50 (17), 2016es_ES
dc.subjectGranular Activated Carbon Treatmentes_ES
dc.subjectBromidees_ES
dc.subjectdisinfection byproductses_ES
dc.subjectcytotoxicityes_ES
dc.subjectgenotoxicityes_ES
dc.titleGranular Activated Carbon Treatment May Result in Higher Predicted Genotoxicity in the Presence of Bromidees_ES
dc.typeartículo original
dc.identifier.doi10.1021/acs.est.6b02508
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro en Investigación en Contaminación Ambiental (CICA)es_ES
dc.identifier.pmid27467860


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