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dc.creatorGutiérrez, José María
dc.date.accessioned2017-03-24T20:57:33Z
dc.date.available2017-03-24T20:57:33Z
dc.date.issued2012-09-15
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/S0041010112000475es_ES
dc.identifier.issn0041-0101
dc.identifier.urihttps://hdl.handle.net/10669/29620
dc.description2082-09-01 Embargo por política editoriales_ES
dc.description.abstractSnakebite envenomings constitute a serious and neglected public health problem. Despite the fact that effective treatment exists, i.e. administration of animal-derived antivenoms, the availability and accessibility of these life-saving immunobiologicals is deficitary in various parts of the world, particularly in sub-Saharan Africa and some regions of Asia. This article discusses some of the problems that need to be circumvented in order to improve the availability and accessibility of antivenoms. The conglomerate of antivenom manufacturers is highly heterogeneous in terms of technological base, qualification of staff, implementation of Good Manufacturing Practices (GMPs), and volume of production. Therefore, improvements in antivenom quality and availability should be based on strategies tailored to the situation of each region or country; in this context, three different scenarios are discussed. Accessibility of antivenoms demands concerted efforts at multiple levels, including raising the awareness of public health authorities on the relevance of the problem, implementing innovative antivenom purchasing schemes, strengthening national distribution channels on the basis of robust epidemiological information, improving the cold chain and the provision of health services in remote rural settings, supporting the correct use of antivenoms, and promoting the involvement of local community organizations in various aspects of prevention and management. These tasks should be envisaged in terms of synergistic, interprogrammatic and intersectorial interventions, with the participation of many players.es_ES
dc.description.sponsorshipUniversidad de Costa Rica//UCR/Costa Ricaes_ES
dc.description.sponsorshipConsejo Nacional de Rectores//CONARE/Costa Ricaes_ES
dc.description.sponsorshipFundación Costa Rica - Estados Unidos para la cooperación//CRUSA/Estados Unidoses_ES
dc.description.sponsorshipNetwork for Research and Traning in Tropical Deseases, Central America//NeTropica/Costa Ricaes_ES
dc.description.sponsorshipPrograma Iberoamericano de Ciencia y Tecnología para el Desarrollo//CYTED/es_ES
dc.language.isoen_USes_ES
dc.sourceToxicon Volumen 60, Número 4. 2012es_ES
dc.subjectSnakebitees_ES
dc.subjectEnvenominges_ES
dc.subjectAntivenomes_ES
dc.subjectAvailabilityes_ES
dc.subjectAccessibilityes_ES
dc.subjectAcceptabilityes_ES
dc.subjectCooperationes_ES
dc.titleImproving antivenom availability and accessibility: Science, technology, and beyondes_ES
dc.typeartículo científicoes_ES
dc.identifier.doi10.1016/j.toxicon.2012.02.008
dc.identifier.doi0041-0101
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.identifier.pmid22781134


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