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dc.creatorLeón Montero, Guillermo
dc.creatorSánchez Céspedes, Laura Vanessa
dc.creatorHernández, Andrés
dc.creatorVillalta Arrieta, Mauren
dc.creatorHerrera Vega, María
dc.creatorSegura Ruiz, Álvaro
dc.creatorEstrada Umaña, Ricardo
dc.creatorGutiérrez, José María
dc.date.accessioned2017-02-27T17:40:13Z
dc.date.available2017-02-27T17:40:13Z
dc.date.issued2011
dc.identifier.citationhttp://www.eurekaselect.com/88787/article
dc.identifier.issn2212-4055
dc.identifier.urihttps://hdl.handle.net/10669/29559
dc.descriptionVersión final embargada hasta 2081-08 por política editoriales_ES
dc.description.abstractThe immune response involves a complex repertoire of innate and adaptive responses to foreign agents in the organism. The present review focuses on the immune response to snake venoms, including those occurring in snakebite accidental envenomation, experimental vaccination and animal hyperimmunization for snake antivenom production. The following aspects are considered: (a) the structural characteristics of snake toxins and their relationship to immunogenicity, (b) the effects that factors such as administration route, venom dose, type of adjuvant, and individual and species characteristics of the immunized animal have on the immune response, (c) the initial venom-induced inflammatory response, (d) the process by which specific antibodies towards individual toxins are produced, and (e) the techniques currently used to evaluate the antibody response. Understanding the immune response to snake venoms is highly relevant for improving antivenom production and for gaining a more complete view of snakebite envenoming.es_ES
dc.description.sponsorshipUniversidad de Costa Rica/[741-A9-003]/UCR/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceInflammation & Allergy - Drug Targets; Volumen 10, Número 5. 2011es_ES
dc.subjectSnake venomes_ES
dc.subjectImmunogenses_ES
dc.subjectImmunizationes_ES
dc.subjectImmune responsees_ES
dc.subjectAntivenomes_ES
dc.subjectSnakebitees_ES
dc.subjectExperimental vaccinationes_ES
dc.subjectSnake toxines_ES
dc.subjectAntivenom productiones_ES
dc.subjectPhospholipaseses_ES
dc.subjectMetalloproteinaseses_ES
dc.titleImmune Response Towards Snake Venomses_ES
dc.typeartículo científico
dc.identifier.doi10.2174/187152811797200605
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.identifier.codproyecto741-A9-003
dc.identifier.pmid21824081


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