| dc.creator | Murakami, Mário T. | |
| dc.creator | Gava, Lisandra M. | |
| dc.creator | Zela, Sandro P. | |
| dc.creator | Arruda, Emerson Z. | |
| dc.creator | Melo, Paulo A. | |
| dc.creator | Gutiérrez, José María | |
| dc.creator | Arni, Raghuvir K. | |
| dc.date.accessioned | 2017-02-22T16:44:59Z | |
| dc.date.available | 2017-02-22T16:44:59Z | |
| dc.date.issued | 2004-12-01 | |
| dc.identifier.citation | http://www.sciencedirect.com/science/article/pii/S1570963904002201 | |
| dc.identifier.issn | 1570-9639 | |
| dc.identifier.uri | https://hdl.handle.net/10669/29546 | |
| dc.description.abstract | Suramin is a highly charged polysulfonated napthylurea that interferes in a number of physiologically relevant processes such as myotoxicity, blood coagulation and several kinds of cancers. This synthetic compound was complexed with a myotoxic Lys49 PLA2 from Bothrops asper venom and crystallized by the hanging-drop vapor diffusion method at 18 °C. The crystals belong to the orthorhombic space group P212121, with unit cell parameters a=49.05, b=63.84 and c=85.67 Å. Diffraction data was collected to 1.78 Å. | es_ES |
| dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo//FAPESP/Brasil | es_ES |
| dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico//CNPq/Brasil | es_ES |
| dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nivel Superior//CAPES/Brasil | es_ES |
| dc.language.iso | en_US | es_ES |
| dc.source | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics; Volumen 1703, Número 1. 2004 | es_ES |
| dc.subject | Suramin | es_ES |
| dc.subject | Myotoxicity | es_ES |
| dc.subject | Lys49 PLA2s | es_ES |
| dc.subject | X-Ray Diffraction | es_ES |
| dc.subject | Snake venom | es_ES |
| dc.title | Crystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA2 from Bothrops asper venom | es_ES |
| dc.type | artículo científico | |
| dc.identifier.doi | 10.1016/j.bbapap.2004.08.009 | |
| dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP) | es_ES |
| dc.identifier.pmid | 15588706 | |
