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dc.creatorMurakami, Mário T.
dc.creatorGava, Lisandra M.
dc.creatorZela, Sandro P.
dc.creatorArruda, Emerson Z.
dc.creatorMelo, Paulo A.
dc.creatorGutiérrez, José María
dc.creatorArni, Raghuvir K.
dc.date.accessioned2017-02-22T16:44:59Z
dc.date.available2017-02-22T16:44:59Z
dc.date.issued2004-12-01
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/S1570963904002201
dc.identifier.issn1570-9639
dc.identifier.urihttps://hdl.handle.net/10669/29546
dc.description.abstractSuramin is a highly charged polysulfonated napthylurea that interferes in a number of physiologically relevant processes such as myotoxicity, blood coagulation and several kinds of cancers. This synthetic compound was complexed with a myotoxic Lys49 PLA2 from Bothrops asper venom and crystallized by the hanging-drop vapor diffusion method at 18 °C. The crystals belong to the orthorhombic space group P212121, with unit cell parameters a=49.05, b=63.84 and c=85.67 Å. Diffraction data was collected to 1.78 Å.es_ES
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo//FAPESP/Brasiles_ES
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico//CNPq/Brasiles_ES
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nivel Superior//CAPES/Brasiles_ES
dc.language.isoen_USes_ES
dc.sourceBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics; Volumen 1703, Número 1. 2004es_ES
dc.subjectSuramines_ES
dc.subjectMyotoxicityes_ES
dc.subjectLys49 PLA2ses_ES
dc.subjectX-Ray Diffractiones_ES
dc.subjectSnake venomes_ES
dc.titleCrystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA2 from Bothrops asper venomes_ES
dc.typeartículo científico
dc.identifier.doi10.1016/j.bbapap.2004.08.009
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.identifier.pmid15588706


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