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dc.creatorGutiérrez, José María
dc.creatorÁvila Agüero, Claudio
dc.creatorCamacho Mora, Zianne
dc.creatorLomonte, Bruno
dc.date.accessioned2016-11-07T19:34:25Z
dc.date.available2016-11-07T19:34:25Z
dc.date.issued1990
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/004101019090080Q
dc.identifier.issn0041-0101
dc.identifier.urihttps://hdl.handle.net/10669/29159
dc.description.abstractA comparative study was performed on some enzymatic and toxic activities of venoms collected from newborn, one-year old, two-years old and adult (more than five-years old) specimens of Lachesis muta stenophrys. There was an increase in lethal, hemorrhagic, edema-forming, myotoxic, proteolytic and phospholipase A2 activities of venoms as snakes aged. The venom of newborn specimens was almost devoid of toxicity. On the other hand, venom from newborn specimens showed the highest coagulant effect of human plasma. Electrophoretic and immunochemical results demonstrated conspicuous differences between venoms of different ages. Observations on the feeding behavior indicated that specimens of L. muta of different ages displayed a similar pattern, characterized by rapid strike and bite, holding the prey until they stopped their movements and swallowing them afterwards. It is concluded that venom of newborn L. muta has very low toxic and proteolytic activities and that it undergoes conspicuous changes during the first year of life.es_ES
dc.language.isoen_USes_ES
dc.sourceToxicon 28(4). 1990es_ES
dc.subjectAginges_ES
dc.subjectAnimalses_ES
dc.subjectBlood Coagulationes_ES
dc.subjectCosta Ricaes_ES
dc.subjectCrotalid Venomses_ES
dc.subjectEatinges_ES
dc.subjectHemorrhagees_ES
dc.subjectHumanses_ES
dc.subjectLethal Dose 50es_ES
dc.subjectMicees_ES
dc.subjectPhospholipases Aes_ES
dc.subjectPhospholipases A2es_ES
dc.subjectSnake venomes_ES
dc.titleOntogenetic changes in the venom of the snake Lachesis muta stenophrys (bushmaster) from Costa Ricaes_ES
dc.typeartículo original
dc.identifier.doi10.1016/0041-0101(90)90080-Q
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES


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