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ArsH protects Pseudomonas putida from oxidative damage caused by exposure to arsenic
(2020-03-23)
The two As resistance arsRBC operons of Pseudomonas putida KT2440 are followed by a downstream gene called arsH that encodes an NADPH‐dependent flavin mononucleotide reductase. In this work, we show that the arsH1 and (to ...
A Metabolic Widget Adjusts the Phosphoenolpyruvate-Dependent Fructose Influx in Pseudomonas putida
(2016)
Fructose uptake in the soil bacterium Pseudomonas putida occurs through a canonical phosphoenolpyruvate (PEP)-dependent sugar transport system (PTSFru). The logic of the genetic circuit that rules its functioning is puzzling: ...
Transcriptional control of 2,4-dinitrotoluene degradation in Burkholderia sp. R34 bears a regulatory patch that eases pathway evolution
(2021-05)
The dnt pathway of Burkholderia sp. R34 is in the
midst of an evolutionary journey from its ancestral,
natural substrate (naphthalene) towards a new xenobiotic
one [2,4-dinitrotoluene (DNT)]. The gene cluster
encoding ...
Low CyaA expression and anti‐cooperative binding of cAMP to CRP frames the scope of the cognate regulon of Pseudomonas putida
(2021-03)
Although the soil bacterium Pseudomonas putida
KT2440 bears a bona fide adenylate cyclase gene
(cyaA), intracellular concentrations of 30,50-cyclic
adenosine monophosphate (cAMP) are barely detectable.
By using reporter ...
Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress
(2021-01-11)
As a frequent inhabitant of sites polluted with toxic chemicals, the soil bacterium and plant-root colonizer Pseudomonas
putida can tolerate high levels of endogenous and exogenous oxidative stress. Yet, the ultimate ...