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Crystal structures and biological activity of 1,1,4-triphenyl-substituted 1,3-enyne compounds
1,3-Enyne structural motifs are versatile building blocks in organic synthesis and occur widely in various natural products with many of them being highly active as cytotoxic macrolides and antitumour antibiotics. This ...
The title compound, C9H7NO2, was prepared by alkynylation of 4-iodonitrobenzene with 1,3-dilithiopropyne in the presence of 1 equivalent of CuI and catalytic amounts of Pd(PPh3)2Cl2. The complete molecule is generated ...
The asymmetric unit of the title homopropargyl alcohol, C20H16OS, contains two independent molecules comprising a hydroxy group, a 3-(2-thiophenyl)- propargylic moiety and two aromatic rings linked to a central carbon atom. ...
Homopropargyl alcohol 5,5-diphenylpent-2-yne-1,5-diol
In the title compound, C17H16O2, the central carbon atom has a distorted tetrahedral geometry [spread of angles = 105.71 (8)–112.75 (9)°] for its bonds to a homopropargylic but-2-yn-1-ol moiety, a hydroxy group and two ...
Homopropargyl alcohol 1,1-diphenylbut-3-yn-1-ol
The asymmetric unit of the title compound, C16H14O, contains one molecule with a central carbon atom having a distorted tetrahedral geometry made of a propargylic fragment, a hydroxy group and two aromatic rings. ...